Flashcards in Skin Biopsy Lab Deck (15):
to make a DX of any swelling of tissue
4 reasons to biopsy..
1. confirm DX before administering potentially harmful drugs
2. determine cause of non-healing wounds
3. quickly determine etiology of aggressive or unusual skin lesions
4. determine cause of lesions that develop during the course of therapy
When should you biopsy?
When lesions are ACTIVE or BEFORE use of a therapy that might alter the histologic appearance of the lesions
What 2 types of drugs may alter the histologic appearance of skin lesions?
It is best to biopsy the ___ spectrum of lesions present.
Where to biopsy?
multiple cutaneous sites that represent the full range of lesions (both 1ry & 2ry)
Be sure to label each sample with the _____ it was collected from.
How do you prepare a site for biopsy?
1. trim hair short (gently)
2. DO NOT surgically prepare the site (disinfect w/ 70% alcohol & let air dry)
Technique to biopsy lesions.
1. multiple samples representative of the range of lesions
2. properly label w/ location
3. always include crusts, if present
Technique for alopecic conditions.
1. collect sample from most alopecic area
2. draw line in direction of hair coat growth
Technique for ulcerative & de-pigmenting lesions.
collect sample from the junctional zone --> margin btwn normal & abnormal skin
Size of punch biopsy for haired skin?
6-8 mm punch
Size of punch biopsy for periocular skin, paw pads, or nasal planum?
4-6 mm punch
Technique for incisional biopsy.
1. take representative sample of the entire lesion + some normal skin
2. elliptical incision --> easier to stitch up