IV - Bone Flashcards Preview

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Flashcards in IV - Bone Deck (47)
1

Bone Stores: Calcium

99%

2

Bone Stores: Phosphorus

85%

3

Bone Stores: Magnesium

65%

4

Unmineralized bone

osteoid

5

Most abundant bone cell

osteocyte

6

Bone resorption cell

osteoclast

7

Bone cell with PTH, vitamin D and estrogen receptors

osteoblast

8

Multinucleated bone cells derived from the pluripotent hematopoietic stem cells

osteoclast

9

Mononuclear cells that synthesize most of the protein in bone

osteoblast

10

Deposits new bone matrix and mineralizes it

osteoblast

11

Trabecular or Spongy Bone

cancellous

12

Compact Bone

cortical

13

Bone: less dense, softer, weaker, less stiff

cancellous

14

Bone: facilitates main functions

cortical

15

Bone: highly vascular, contains marrow

cancellous

16

Bone: 80% of weight of the skeleton

cortical

17

Bone: site of hematopoiesis

cancellous

18

Bone: affected by osteoporosis

cancellous

19

Resorbs bone

osteoclast

20

Bone: pluripotent mesenchymal stem cells

osteoprogenitor cells

21

Synthesize, transport and arrange bone matrix

osteoblast

22

Bone: derived from hematopoietic progenitor cells

osteoclast

23

Bone: ruffled borders along its membrane to increase cell surface area

osteoclast

24

Bone: detect mechanical forces and translate them into biological activities

osteocyte

25

Functional unit of compact bone

osteon/Haversian system

26

Carries blood vessels and nerves through the osteon

Haversian canal

27

"Little layer" of bone matrix between concentric rings of osteocytes

lamellae

28

Houses osteocytes

lacunae

29

Houses osteoclasts

Howship's lacunae

30

Protoplasmic extensions from osteocytes by which maintenance of bone is performed

canaliculi

31

Connects one Haversian canal to another

Volkmann's canal

32

Developing and growing bones, hard callus of bone fractures, immature/primary/bundle bone, newly calcified

woven bone

33

Remodeled from woven bone, adult bone, mature/secondary bone

lamellar bone

34

80% of lamellar bone, thick outer region beneath periosteum, cortical bone

compact bone

35

20% of lamellar bone, inner region, adjacent to marrow cavities, spongy/trabecullar/medullary bone

cancellous bone

36

Intramembranous Ossification

mesenchyme → osteoprogenitor cells → osteoblasts → osteoid

37

Endochondral Ossification

erosion of pre-existing hyaline cartilage by osteoblasts → osteoid

38

Type I collagen defect

Osteogenesis Imperfecta

39

Lack of GH

Pituitary Dwarfism

40

Excess GH in adolescents

Gigantism

41

Excess GH in adults

Acromegaly

42

Permanent flexion contracture of the hand at the wrist (claw-like deformity) commonly caused by a fracture in the elbow or upper arm

Volkmann's Contracture

43

Artery occluded in Volkmann's Contracture

brachial artery

44

Muscles affected in Volkmann's Contracture

flexor digitorum profundus, flexor pollicis longus

45

Most common primary bone cancer

Osteosarcoma

46

Sun-burst appearance on x-ray

Osteosarcoma

47

Area of new subperiosteal bone that is created when a new lesion raises the periosteum away from the bone

Codman Triangle