V - Blood Flashcards Preview

Histology > V - Blood > Flashcards

Flashcards in V - Blood Deck (77)
Loading flashcards...
1

Blood: no nucleus/mitochondria, anaerobic glycolysis

erythrocytes

2

Protein that maintains the biconcave shape of the RBC

spectrin

3

Life span of adult RBCs

120 days

4

Life span of fetal RBCs

90 days

5

Life span of reticulocytes

1-2 days

6

Point mutation in the gene for the beta hemoglobin chain in RBCs

Sickle Cell Anemia

7

Multilobulated nucleus (2-5 lobes) connected by thin strand of nuclear materials (chromatin) with light staining very fine granules, phagocytic

neutrophils

8

Most abundant type of leukocyte (70%)

neutrophils

9

Has small golgi apparatus, sparse mitochondria and ribosomes, absent RER

neutrophils

10

Lifespan of neutrophils

1-4 days, half-life of 6-8 hours in blood

11

Hereditary immune system disorder that affects neutrophils

Chronic Granulomatous Disease

12

Shows the average level of blood glucose over the past 3 months

HbA1c

13

Bilobulated nucleus with numerous pink-orange granules, 1-3% of leukocytes

eosinophils

14

Highly involved in immune response against parasites especially helminths

eosinophils

15

Granulocyte that controls mechanisms in anaphylaxis and asthma

eosinophils

16

Allergic inflammatory condition of the esophagus that presents as heartburn and food impaction

Eosinphilic Esophagitis

17

Least common leukocyte (0.01-0.3%)

basophils

18

Contains large cytoplasmic granules which obscure the nucleus under light microscopy

basophils

19

Granulocyte that is important in immediate hypersensitivity reactions (type I) and anaphylaxis

basophils

20

Releases histamine, proteoglycans (heparin, chondroitin) and proteolytic enzymes (elastase, lysophospholipase)

basophils

21

Basophils in tissues

mast cells

22

Hematologic indicator of lead poisoning

basophilic stippling

23

Smallest leukocytes

lymphocytes

24

3 Main Types of Lymphocytes

T-cell, B-cell, Natural Killer Cells

25

Lymphocytes involved in cell-mediated immunity

T-cells

26

Lymphocytes responsible for humoral immunity

B-cells

27

Recognize non-self antigens during antigen presentation

T-cells and B-cells

28

Defends the host from tumors and virus infected cells

Natural Killer Cells

29

Natural Killer cells distinguish infected and cancerous cells from normal cells by recognizing changes in a surface molecule

MHC (major histocompatibility complex) Class I

30

Lymphocytes: lysis of virally infected cells and tumor cells

NK cells