Flashcards in kef 30 pathiseis periferikou ns Deck (31)
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1
ti einai i baleriani ekfilisi
ekflisisi twn nevraksonwn twn nevrikwn kitarwn
2
xaraktiristiki okseia/ipokseia nevropatheia
guillain barre
3
kinitikes nevropatheies
guillain barre(flegmwnwdi apomielinwtiki) ,porfiria diftheritida kai molivdo
4
aisthitikes nevropatheies
apo lepra ,sd(aksoniki nevropatheia),amiloeidwsi ,elleipsib12(aksoniki nevropatheia)
5
sti nevroapraksia exoume _ enw stin aksonotmisi exoume_
tmimatiki apomielinwsi pou nevrou logo piesis,,,,,,,aksoniki ekfilisi(se oliki fasi nevronotmisi)
6
poio nevro perna apo ton tarsiaio solina kai poies oi kiries diakladwseis tou
to knimiaio/.... esw kai eksw pelmatiaio ,
7
peroniaia miiki atrofia nosos cmt i klironimiki kinitiki kai aisthitiki nevropatheia(hmsn)
provlima stin mielini(gonidia pmp-22,po) epomenos apomielinwsi,atrofia sta katw akra podia pelargou kai koilopodia
8
oikogeneis amiloeidikes polinevropatheies
epodines paresthisies sta katw akra,apoleia mikrwn aisthitikwn nevrwn prwta (thermokrasias kai ponou),meta diataraxi se ola ta oidi periferikwn nevrwn,(diataraxes aftonomou,provlima sta gonidia amiloeidikwn prwteinwn: transthiretinis(ttr) ,apolipoprwteini a1,gkelsonini
9
33% twn asthenwn 1-4 vdomades prin tin gb emfanizoun loimwksi apo poia mikrovia einai?
kampilovaktiridio tis nistidos(diarroiko sindromo),cmv,ebv,mikoplasma tis pnevmonias,ipatitida,hiv
10
pathan vlavi guillain barre(okseia flegmwnwdis apomielinwtiki polirizonevropatheia)
diaxiti poliestiaki tmimatiki apomielinwsi se ola ta periferika nevra ,sto simeio tis apomielinwsis exoume lfegmonwdi diithisi apo lemfokitara kai sto telos aksoniki ekfilisi
11
simtwmata gb
okseia nevromiiki paralisi,aniousa proodeftiki miiki adinamia mexri ofthalmokinitikous ,apo ta katw akra mexri ton avxena,,katargisi tenwntiwn antanaklastikwn apo tis prwtes imeres, paraisthisies kai mialgies
12
ergastiriaka evrimata gb
leukomatokittarikos dixasmos so eny(avksimeno lefkwma,fisiologika kittara),se ilektrofisiologiko elegxo exoume meiomeni taxitita agwgis k F kimma se eksetaseis aimatos exoume: antiswmata kata gaggliosidwn GM1 (25% twn periptwsewn),tke,lefka,ipatika ,meiwsi na(provlima stin antidiouritiki)
13
klinikes parallages gb
sindomo miller fisher(ekswteriki ofthalmopligia ataksia kai katargisi tenontiwn antanaklastikwn) : ston oro IgG enanti gaggliosidiou GQ1b ,
14
poreia gb
egkatastasi 1-4 w
statheropoisi 2-4 w
apokatastasi 6m -2y
15
therapeia gb
plsamaferesi 2-4 siedries
iv anososfairini 0,4g/kg gia 5d
16
xronia flegmonwdis apomielinwtiki polirizonevropatheia CIDP ,poia einai ta ipoxrewtika klinika kritiria diagnwsis
proodeftiki miiki adinamia(>2 months)
meiwsi i katargisi antanaklastikwn
miiki adinamia kai periferika aisthitika simptwmata
17
xronia flegmonwdis apomielinwtiki polirizonevropatheia,ergastiriaka (therapeia ;prednizoni kai plasmaferesi)
prwteini eny >45mg/ml kai kittara therapeia prednizoni
18
poies nosoi kanoun paraprwteinemia(avksisi monoklwnikou antisomatos dld anososferines apo plasmatokitara)
mielwma,lemfwma,makrosfairinaimia ,sistimatiki amiloeidwsi,aftes oi paraprwteines Ig(M-->MAG,G,A) exoun antigona stoxous
19
poreia makrosfairinaimias tou waldenstrom
kakoithi lemfokittara ston mielo ,ekrinoun igM monoklwniki prwteini , afti kanei vareia simmertriki aisthitiki nevropatheia (paraisthisies algos +krampes ,anti MAG drastiriotita
20
prosvoli periferikou nevrikou ti exoume me poiu katastrofi
katastrofi kitarikou swmatos:nevrwnopatheia eite kinitiki(prwsthio keras) eitai aisthitiki(nwtiaio gagglio) ,..aksonikes nevropatheies vlavi stous nevraksones kinitikous i aisthitikous....apomielinwtikes nevropatheies elitro mielinis schwann-->parempidisi agwgimotitas miiki adinamia ipies diataraxes aisthitikotitas (meiwsi taxititas agwgis)...meiktes nevropatheies(aksoniki ekfilisi tmimatiki apomielinwsi)
21
nevropatheies aksonikes
idiopathis,metabolikes :diavitiki ipothireoeidiki nefriki aneparkeia ,toksikes ,steritikes alkool b12 e, sistimatikes sarkoeidwsi likos ,paraprwteinaimikes paraneoplasmatikes
22
nevropatheies apomielinwtikes
FLEGMONWDEIS gb cidp poliestiaki kinitiki nevropathiea paraprwteinaimikes KLIRONOMIKES cmt t1 kai tipou 2 TOKSIKES,MITOXONDRIAKES,LOIMWDEIS ,LEMFWMA
23
polinevropatheia :
simmetriki prosvoli twn periferikwn nevrwn apo toksikes metavolikes i klironomikes astheneies....ekfrazete eitai periferikou tipou (ganti kaltsa ) eitai kentromielikou tipou
24
ti mporei na kanei pagidevsi nevrou
ipothireieidismos ,akromegalia ,arthropatheies ,kai katastaseis me genikevmeno eidima
25
aisthitikokinitikes nevropatheies
sd ,nefriki aneparkeia alkoolismo ipith
26
aftonomes nevropatheies
diaviti + prwima stadia amiloeidwsis
27
sindromo karpiaiou solina logoi:(nevropatheia apo pagidevsi)
topiki pathologiki diergasia : travma ,lipwma kisti osteorthritikes alloiwseis ,se sxesi me sistimatikes katastaseis :egkimosini ipoth,akromegalia ,amiloeidwsi , idiopathes
28
kliniki eikona sindromo karpiaiou solina
ponos kai paresthisies 3 prwtwn daktilwn kai palamis,mporei na antanakla kai kentrikotera,ipoxoroun me kremasma kai tinagma xeriwn,miiki adinamia atrofia ipaisthisia
29
poio nevro kanei paraisthitiki miralgia
to eksw dermatiko nevro tou mirou
30
