What does the lymphatic system collect? (3)
Interstitial fluids, absorbed fats, leaked proteins
What makes the largest % of lymph (out of all the ones that it collects)?
Where does the lymph system return to?
Where does the lymph system NOT exist in? (everywhere EXCEPT what places) (4)
Cartilage, cornea, CNS, epidermis
What does the lymph system not have?
Where is the lymph system open-ended? Close-ended?
Open-ended: periphery Close-ended: proximally
Origin of lymph is from the ________
What are 3 features of the lymph capillaries?
1. Cells overlap 2. Very thin walls (same wall layers as other vessles but one endothelial cell think) 3. No tight junctions
What makes sure the lymph vessles "stay in place"?
What are 4 features of the lymphatic collecting vessels?
1. Thicker walls 2. Presence of valves 3. Superficial: travel with larger veins 4. Deep: travel with larger arteries
What do the valves on the lymphatic collecting vessles do?
What happens to antigens if they are present in the body?
What "type" of lymph is going in from the periphery? What "type" is going out of the hilum?
"dirty" lymph in from periphery "Clean" lymph out from hilum
Lymph from intersitial spaces travels to ---> 3 things
Lymphatic coll. vessles
At least one lymph node
Gathering of lymph nodes flow to what 3 things?
Lymphatic trunks Lymphatic ducts Venous system
Immunity is the response of cells and tissues to ______
There are two types of immune reactions- what are they?
Innate response Adaptive response
What are 3 features of the innate response type of immune reactions?
1. No requirement for previous exposure 2. Non-specific response 3. Immediate and rapid response
What are 3 features of the adaptive response type of immune reactions?
1. Requires previous exposure 2. Recognition of diverse antigens 3. Delayed response
The innate immune response provides the " _____"
First line of defense
The innate immune response consists of cells that __, _____, or present ____.
Recruit, phagocytose, or present antigens
What are the two antigen-presenting cells (APCs)? What do they do?
Macrophages and dendritic cells - Trigger adaptive immune resonse
What is this a structure of?
The lymph moves in one direction in the lymphatic collecting vessels- which direction is this?
Left to right
Name these innate immune response cells from left to right- also which two are APCs?
Mast cells, granulocytes, macrophages, dendritic cells
The macrophages and dendritic cells are antigen-presenting cells
In adaptive immune response, what are the main cells involved?
What are the two types of lympocytes?
B and T lymphocytes
What is the type of immune response of B lymphocytes and what are they activated by?
Humoral (antibody) immune response
Activated by: "externalized" antigens
What type of immune response will T lymphocytes have? What are they activated by?
Cell-mediated immune response
Activated by "internalized" antigens APCs needed
What are the two effectors B lympthocytes?
1. Plasma cells
2. B memory cells