Flashcards in Lecture 1 - Pituitary Deck (24):
the anterior pituitary is derived from _____. the posterior pituitary is derived from _____;
the pituitary gland is located in the _____
oral ectoderm (Rathke's pouch);
TRH stimulates the release of what
dopamine _____ prolactin secretion. prolactin inhibits ______
most common pituitary tumor>?
prolactinoma (diagnosed early);
GH tumor less common, diagnosed late
mass effects of pituitary adenomas:
_____ (visual), ____pituitarism, headache
bitemporal hemianopia, hypo
prolactin may be increased in response to _____ antagonists; they may also be increased in ___thyroidism
hypo (due to increased TRH)
presentation of prolactinoma:
in women: ____, ____, ____ bone density due to ____ in estrogen
galactorrhea, amenorrhea, decreased;
prolactinoma in men:
_____ and _____
low libido, infertility
treatment of prolactinoma: _____ is first line. examples = ?
cabergoline, bromocriptine, pergolide
GH is released in a ____ manner, usually at _____.
what mediator is measured to look at GH levels?
this mediator causes ____, _____ resistance, and ____ growth
lipolysis, insulin, muscle
____ in kids, ____ in adults; typically due to _____
pituitary adenoma (large )
large ____ and ____, frontal _____, excessive ____, impaired ____ tolerance
glucose (2ndary type 2 DM)
increased serum ____. failure to suppress serum ____ following oral _____
____ is first line.
if not cured, treat with _____, a somatostatin analog or _____, a GH receptor antagonist
increased risk of ____ cancer.
death due to ____
ADH is synthesised in the ____.
oxytocin is synthesized in the ____;
both are transported to the posterior pit via ____
ADH release is stimulated by ____osmolality, ____volemia, and nausea
characterized by ___volemic ___natremia with ____ urinary Na exretion
Urine osmolality is _____ than serum osmolality.
with water retention, aldosterone levels ____ and ____ levels increase
treatment of SIADH:
_____ is a arginine vasopressin receptor antagonist. ____ is a selective V2 receptor antagonist
from ectopic ADH such as ____ cancer;
small cell lung;
urine osmolality is ____ than serum osmolality;
___natremia, polyuria, polydipsia.
specific gravity is (low or high)
hyperosmotic volume _____