Lecture 12.2 Flashcards Preview

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Flashcards in Lecture 12.2 Deck (3):
1

What was jake (jamacian Ginger)

80-85% alcohol - legal in prohibition, caused motor control disordered and inpotence when TOPC was added

2

MPTP has also been the cause of a ..

gait problem - a by product of incorrectly synthesising drugs

3

MPTP is not toxic, but can cross the ___

Once inside the brain, can form ___

___ kills dopamine-producing _____ in substantia nigra

MPTP is not toxic, but can cross the BBB

Once inside the brain, can form MPP+

MPP+ kills dopamine-producing neurons in substantia nigra (high affinity uptake process)