lecture 39 terms

Question 1

collection of symptoms is called?

Answer 1

syndromes

Question 2

genetic defects that result in an increased susceptibility to infection

manifest in infancy and early childhood, or later in life

treatment-correct defective gene, hematopoietic stem cell transplant, control and treat infection

Answer 2

primary or congenital immunodeficiencies

Question 3

immunodeficiencies are not inherited diseases but develop after birth due to malnutrition and treated with immunosuppressive drugs

Answer 3

secondary or acquired immunodeficiencies

Question 4

the principal consequence of immunodeficiency is due to?

Answer 4

increased susceptibility to infection

Question 5

these types of infections occur in immunodeficient patients, those with defects in cellular immunity but would otherwise be eliminated by healthy persons

Answer 5

opportunistic infections

Question 6

these types of diseases are passed down through families through one of the X or Y chromosomes. X and Y are sex chromosomes. Sex-linked is generally X-linked diseases and hence occur in males only! The mother is always a carrier

Answer 6

sex linked diseases

Question 7

this is one of several ways that a trait, disorder, or disease can be passed down through families. An autosomal recessive disorder means two copies of an abnormal gene must be present in order for the disease or trait to develop.

Answer 7

autosomal recessive

Question 8

destroys the hydrogen peroxide that may be produced by host cells from the residual reactive oxygen radical, superoxide.

Answer 8

catalase

Question 9

Successful in the treatment of SCID with ADA deficiency, Wiskott-Aldrich syndrome, bare lymphocyte syndrome, and LADs (monogeneic defects)

Answer 9

hematopoietic stem cell transplantation

Question 10

in stem cells - ADA deficiency and X-linked SCID. Major problem - Leukemia

Answer 10

gene therapy