Lymphatic System I & II Flashcards Preview

Histology Post Midterm > Lymphatic System I & II > Flashcards

Flashcards in Lymphatic System I & II Deck (71)
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1

How are the functions of the lymphatic system carried out by?

Cells
effector molecules
tissues
organs

2

what cells arise from lymphoid stem cells?

T lymphocytes
NK cells
B lymphocytes -- plasma cells

3

what are the two types of T cells?

Helper CD 4+
Cytotoxic CD 8+

4

what do helper CD 4 activate?

B lymphocytes
CD 8+ with IL-2 production

5

what types of lymphocytes are capable of recirculation?

T cells - 60-70% of circulating lymphocytes

6

Where are B cells produced?

bone marrow

7

what do NK cells attack?

virally infected cells
cancer/tumor cells

8

what types of cells carryout innate responses?

neutrophils
macrophages
mast cells
NK cells

9

what are the characteristics of innate responses?

fast and non specific
does not produce memory cells

10

What cells are involved in adaptive response?

B and T cells - depends on the initial recognition of antigens

11

what are the characteristics of adaptive responses?

slower and specific
produces memory cells

12

when is antibody mediate immunity (humoral immune response) important?

bacterial infections

13

what cells are involved in humoral immune responses? what are the effectors?

helper T cells
B cells
plasma cells

Immunoglobin molecules

14

When is cell mediated immunity important?

viral and fungal infections - involved in the rejection of transplanted organs and tissue grafts

15

what are the cells involved in cell mediated immunity? what are the effectors?

Cytotoxic T cells

T cells (effector)

16

what is the characteristic of diffuse, loose lymphoid tissue?

few lymphocytes present

initial immune response
found in lamina propria
intercepts antigen
no capsule

17

what is the characteristic of diffuse, dense lymphoid tissue?

many lymphocytes are present

contained in meshwork of reticular fibers
No capsule

18

what does the GC indicate?

lymphatic tissue response to antigen

19

what does a primary nodule consist of?

small lymphocytes
not ever exposed to antigen
found in newborns only

20

what does a secondary nodule consist of?

germinal cortex (GC)

21

what is the germinal cortex?

where lymphocytes undergo proliferation

22

what is a follicular dendritic cell?

Not an antigen presenting cell
help keep the antigen-antibody complex in place

23

what is the major cell found in lymphoid nodules?

B lymphocytes

24

what cells are found around the periphery of the lymphoid nodules?

T cells

25

where does the thymus originate from?

3rd pharyngeal pouch
epithelium?

26

what is important to note about the thymus?

no afferent lymphatics - just efferent

why? - because there is no filter, just production and migration through efferent

27

what type of cells make up the epithelial component of the thymus?

ERC - epithelial reticular cells

28

what are thymocytes?

immature T lymphocytes

29

what are the parenchyma of the thymus?

Cortex and medulla

30

what is in the cortex?

immature T lymphocytes = thymocytes
ERCs