MAGNESIUM Flashcards
(76 cards)
4th most abundant [?] in the body
After
cation
Na, K, Ca
2nd most abundant [?]
After[?]
intracellular ion
K
Amount in the body:
24g
distributed in primarily in the:
bones (53%)
intracellularly (46%)
bound to ATP (80%)
extracellularly (<1%)
serum magnesium (extracellular) is further divided into:
protein bound (30%)
ionized or free (55%) - readily available
complexed with other molecules such as phosphate and citrate (15%)
bones
(53%)
intracellularly
(46%)
bound to ATP
(80%)
extracellularly
(<1%)
protein bound
(30%)
ionized or free - readily available
(55%)
complexed with other molecules such as phosphate and citrate
(15%)
– most commonly used cofactor
Magnesium
Cofactor for
> 300 enzymes
Cofactor for > 300 enzymes, including those involved in:
- Glycolysis – breakdown of glucose
- Neuromuscular transmission
- Synthesis of CHO, CHON, lipids & nucleic acids
- Release of and response to certain hormones
[?] of dietary magnesium is absorbed in the [?]
20 to 65%
small intestines
overall regulation like the other electrolytes is a responsibility of the
kidney
Non-protein bound magnesium is readily filtered by the [?]
glomerulus
25 to 30% is reabsorbed in the
proximal convoluted tubules
Majority: 50 to 60% in the [?].
ascending loop of Henle
Only 2 to 5% is reabsorbed in the [?].
distal convoluted tubules
The renal threshold of magnesium is
0.60 to 0.85 mmol/L or mEq/l
Normal serum conc:
Approximately [?]of filtered magnesium is excreted in the urine per day.
6%
