Male Sex Hormones Flashcards
(12 cards)
What effect do androgens have on masculinization?
Androgens can cause masculinization
This refers to the development of male physical characteristics.
In which patients may androgens be used?
Castrated adults and those who are hypogonadal due to pituitary or testicular disease
Hypogonadism refers to reduced hormone production by the gonads.
What is the effect of androgens on spermatogenesis in normal males?
Androgens inhibit spermatogenesis
Spermatogenesis is the process of sperm cell development.
What type of effect do androgens have?
Anabolic effect
Anabolic effects promote muscle and tissue growth.
Are androgens effective in treating impotence and impaired spermatogenesis?
No, unless there is associated hypogonadism
Impotence refers to the inability to achieve or maintain an erection.
What can occur when androgens are given to patients with hypogonadism?
Normal sexual development but not fertility
Gonadotrophins are needed for fertility.
What is cyproterone acetate used for?
Severe hypersexuality and sexual deviation
It is an anti-androgen medication.
What warning is associated with cyproterone acetate?
MHRA warning regarding meningioma
Meningioma is a type of brain tumor.
What is finasteride used for?
Enlarged prostate, BPH, and balding
BPH stands for benign prostatic hyperplasia.
What disorders can finasteride cause?
Impotence, libido and ejaculation disorders, breast tenderness
These are potential side effects of the medication.
What does finasteride inhibit?
The conversion of testosterone into dihydrotestosterone
Dihydrotestosterone is a potent androgen involved in prostate growth.
What serious side effects can finasteride cause?
Suicidal thoughts, depression, and breast cancer
These are rare but serious side effects reported with finasteride use.