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Male Sex Hormones Flashcards

(12 cards)

1
Q

What effect do androgens have on masculinization?

A

Androgens can cause masculinization

This refers to the development of male physical characteristics.

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2
Q

In which patients may androgens be used?

A

Castrated adults and those who are hypogonadal due to pituitary or testicular disease

Hypogonadism refers to reduced hormone production by the gonads.

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3
Q

What is the effect of androgens on spermatogenesis in normal males?

A

Androgens inhibit spermatogenesis

Spermatogenesis is the process of sperm cell development.

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4
Q

What type of effect do androgens have?

A

Anabolic effect

Anabolic effects promote muscle and tissue growth.

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5
Q

Are androgens effective in treating impotence and impaired spermatogenesis?

A

No, unless there is associated hypogonadism

Impotence refers to the inability to achieve or maintain an erection.

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6
Q

What can occur when androgens are given to patients with hypogonadism?

A

Normal sexual development but not fertility

Gonadotrophins are needed for fertility.

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7
Q

What is cyproterone acetate used for?

A

Severe hypersexuality and sexual deviation

It is an anti-androgen medication.

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8
Q

What warning is associated with cyproterone acetate?

A

MHRA warning regarding meningioma

Meningioma is a type of brain tumor.

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9
Q

What is finasteride used for?

A

Enlarged prostate, BPH, and balding

BPH stands for benign prostatic hyperplasia.

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10
Q

What disorders can finasteride cause?

A

Impotence, libido and ejaculation disorders, breast tenderness

These are potential side effects of the medication.

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11
Q

What does finasteride inhibit?

A

The conversion of testosterone into dihydrotestosterone

Dihydrotestosterone is a potent androgen involved in prostate growth.

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12
Q

What serious side effects can finasteride cause?

A

Suicidal thoughts, depression, and breast cancer

These are rare but serious side effects reported with finasteride use.

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