Micro and Macro nutrient digestion Flashcards

1
Q

what are the three products that result from a-amylase breaking down the a 1-4 glycosidic bonds in starch?

A
  1. maltose
  2. maltotriose
  3. alpha-dextrins
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2
Q

Is starch digested in the stomach?

A

No, salivary amylase is inactivated in acidic environments. Starch digestion begins in the mouth, paused in the stomach, and then is further digested in the small intestine.

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3
Q

what are the two areas of the digestive tract that produce/secrete alpha amylase?

A

salivary glands and pancreas (the latter is secreted into the small intestine)

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4
Q

What are the two enzymes that can break down a 1-4 glycosidic bonds?

A

sucrase and alpha amylase

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5
Q

How are glucose molecules moved from the intestinal lumen into the enterocytes of the small intestine?

A

They are absorbed via the sodium-glucose transporter on the apical surface of the enterocytes (2 Na along with every 1 Glu)

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6
Q

Excess glucose can be stored within the liver as _________

A

glycogen

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7
Q

Once glucose is inside an enterocyte, what kind of transporter moves the glucose through the basolateral membrane and on into the bloodstream?

A

GLUT-2 transporter

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8
Q

Lipase enzymes hydrolyse triglycerides into what two component parts?

A

Fatty acids and di-glycerides

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9
Q

In the process of fat digestion, where do micelles go (within the enterocyte) to assist with the synthesis of triglycerides?

A

the endoplasmic reticulum and Golgi apparatus

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10
Q

Lipids enter the enterocyte as _______ and exit the basolateral aspect of the cell into the lymphatic system as __________

A

Micelles, chylomicrons

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11
Q

__________ are the lymphatic vessels of the small intestine (found inside each villus) that aid with the absorption of fat

A

Lacteals

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12
Q

What type of movement/contraction in the stomach helps to break up fat globules into smaller droplets?

A

Segmentation

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13
Q

what converts pepsinogen into its active form of pepsin?

A

The presence of acid in the stomach (HCl released by parietal cells leads to low pH)

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14
Q

Name the two primary pancreatic proteases

A

Trypsin and chymotrypsin

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15
Q

The pro-enzymes trypsinogen and chymotrypsinogen are activated by which enzyme?

A

Enterokinase- secreted by the mucosal membrane (brush border) of the duodenum

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16
Q

What kind of bonds do trypsin and chymotrypsin break down?

A

Peptide bonds in proteins

17
Q

Absorption of amino acids is dependent on the electrochemical gradient of ______ across the epithelium.

A

sodium

18
Q

Vitamins can often act as ___-__________ in metabolic pathways

A

co-enzymes

19
Q

Fat soluble vitamins are stored in the ______ and __________ tissues for future use

A

liver, adipose