Flashcards in Micro: bacterial meningitis Deck (29):
Main virulence factor for bugs that cause meningitis.
Capsule: allows crossing the BBB
#1 cause of all bacterial meningitis
3 major bugs that cause bacterial neonatal meningitis.
3 main bugs that cause bacterial meningitis in infants and children.
Strep pneumo (main in elderly)
N. meningitidis (main in teenagers)
Common manifestations indicative of meningococcal meningitis on physical exam.
Nuchal rigitidy (in responsive patients)
Gram stain and hemolysis pattern of a CSF sample in a patient with pneumococcal meningitis.
Gram (+) diplococci
2 combo therapies for pneumococcal meningitis
Ceftriaxone + ampicillin
Ceftriaxone + vancomycin (if prevalence of resistant srep in over 2% in the community)
Gram stain of CSF in a patient suspected of having meningococcal meningitis.
Gram (-) diplococci
Major complication of meningococcal meningitis.
Prophylaxis for people exposed to a patient with meningococcal meningitis.
Serotype of N. meningitidis not found in the meningococcal vaccine.
Gram stain of a CSF sample from a patient suspected to have H. influenzae meningitis.
Gram (-) pleomorphic coccobacilli
Type of agar that allows the growth of H. influenzae.
Major sign on PE that a neonate has meningitis.
Hemolysis pattern of group B strep.
Gram stain of neonatal meningitis patient infected with E. coli and the major virulence factor.
Gram (-) rod
K1 capsular antigen
Gram stain on a neonate with meningitis caused by Listeria and mechanism of transmission from mother to child.
Gram (+) rod
Diagnosis of L. monocytogenes based on plate growth
(+) CAMP test (also used for Strep a.)
Gram stain of C. tetani and botulinum
Gram (+) rod
-anaerobe spore forming
Major symptoms of botulism
Flaccid paralysis (floppy baby)
Main thing to remember when treating clostridium species.
Never give an antibiotic, give antitoxins. Also don't close wounds infected by C. tetani because the oxygen will help kill the bacteria.
Major non-treponemal test to look for Neurosyphilis
Major condition caused by neurosyphilis
Which stage of Lyme disease causes Neuroborreliosis?
-causes cranial nerve palsies
Hawaii and Rat pee
Veterinarian or farmer handling aborted animal fetuses.
What is unique about meningitis caused by TB?
Most meningitis is fast but TB meningitis is gradual onset mainly because it is a reactivation from a previous infection.