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Flashcards in Micro: bacterial meningitis Deck (29):
0

Main virulence factor for bugs that cause meningitis.

Capsule: allows crossing the BBB

1

#1 cause of all bacterial meningitis

Strep pneumo

2

3 major bugs that cause bacterial neonatal meningitis.

Strep agalactiae
E. coli
Listeria

3

3 main bugs that cause bacterial meningitis in infants and children.

Strep pneumo (main in elderly)
N. meningitidis (main in teenagers)
H. influenzae

4

Common manifestations indicative of meningococcal meningitis on physical exam.

Petechial Rash
Kernig Sign
Brudzinski sign
Nuchal rigitidy (in responsive patients)

5

Gram stain and hemolysis pattern of a CSF sample in a patient with pneumococcal meningitis.

Gram (+) diplococci
Alpa hemolysis

6

2 combo therapies for pneumococcal meningitis

Ceftriaxone + ampicillin

Ceftriaxone + vancomycin (if prevalence of resistant srep in over 2% in the community)

7

Gram stain of CSF in a patient suspected of having meningococcal meningitis.

Gram (-) diplococci

8

Major complication of meningococcal meningitis.

Waterhouse-Friedrichsen syndrome
-adrenal hemorrhage

9

Prophylaxis for people exposed to a patient with meningococcal meningitis.

Rifampin

10

Serotype of N. meningitidis not found in the meningococcal vaccine.

B

11

Gram stain of a CSF sample from a patient suspected to have H. influenzae meningitis.

Gram (-) pleomorphic coccobacilli

12

Type of agar that allows the growth of H. influenzae.

Chocolate agar

13

Major sign on PE that a neonate has meningitis.

Bulging fontanelle

14

Hemolysis pattern of group B strep.

Beta hemolysis

15

Gram stain of neonatal meningitis patient infected with E. coli and the major virulence factor.

Gram (-) rod

K1 capsular antigen

16

Gram stain on a neonate with meningitis caused by Listeria and mechanism of transmission from mother to child.

Gram (+) rod

Crosses placenta

17

Diagnosis of L. monocytogenes based on plate growth

Cold selection

(+) CAMP test (also used for Strep a.)

18

Gram stain of C. tetani and botulinum

Gram (+) rod
-anaerobe spore forming

19

Major symptoms of botulism

Flaccid paralysis (floppy baby)
Constipation

(descending paralysis)

20

Main thing to remember when treating clostridium species.

Never give an antibiotic, give antitoxins. Also don't close wounds infected by C. tetani because the oxygen will help kill the bacteria.

21

Major non-treponemal test to look for Neurosyphilis

VDRL

22

Major condition caused by neurosyphilis

Tabes Dorsalis

23

Which stage of Lyme disease causes Neuroborreliosis?

2nd stage
-causes cranial nerve palsies

24

Hawaii and Rat pee

Leptospira
(spirochete)

25

Veterinarian or farmer handling aborted animal fetuses.

Brucellosis

26

Acid-fast bacilli

Mycobacterium t.

27

What is unique about meningitis caused by TB?

Most meningitis is fast but TB meningitis is gradual onset mainly because it is a reactivation from a previous infection.

28

What is the gram stain and tests for Nocardia?

Gram (+) rods
Catalase (+)

symptoms result from location of abscess