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Flashcards in Microbiology pt.2 Deck (143)
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1

What type of vaccine uses a live virus that has been modified? What are some examples of live virus vaccines?

Live attenuated vaccines:
MMR, Sabine polio, VZV, yellow fever, small pox, intranasal influenza

2

What is the DNA structure of most DNA viruses? What are the exceptions?

double stranded and linear
Exceptions:
- parvovirus (ssDNA)
- papilloma, polyoma, hepadna(circular)

3

When should live virus vaccines be considered for HIV positive pts?

- rotavirus for all infants with HIV
- if CD4 >200, can give MMR, varicella
- not recommend: intranasal flu, herpes zoster

4

Which viral families do not have an envelope? (8)

DNA: papilloma, adeno, parvo, polyoma
RNA: calici, picorna, reo, hepe

5

What is the treatment for the diff. herpes virus?

HSV 1, 2, VZV: acyclovir, valacyclovir, famciclovir

CMV: gangiclovir, foscarnet (if gang doesn't work)

6

What group of pts is prone to esophagitis caused by CMV?

AIDS (CV4

7

Where is the latent herpes infection found in the body?

HSV1: trigeminal ganglion
HSV2: sacral ganglion
VZV: dorsal root or trigeminal
CMV: mononuclear cells
EBV: B cells

8

What are Downey cells

T cells that respond to an EBV infection (atypical lymphocytes; foamy cytoplasm)

9

Which DNA virus is associated with each of the following?
- erythema infectiosum (5th disease)

parvovirus B19

10

Which DNA virus is associated with each of the following?
- heterophile-positive mononucleosis

EBV

11

Which DNA virus is associated with each of the following?
- can cause conjunctivitis or diarrhea

adenovirus

12

Which DNA virus is associated with each of the following?
- enlarged cell with "owl eye" inclusions

CMV

13

Which DNA virus is associated with each of the following?
- identified with pap smear

human papilloma virus

14

Which DNA virus is associated with each of the following?
- milkmaid's blisters

cowpox (vaccinia virus; part of poxvirus)

15

Which DNA virus is associated with each of the following?
- burkitt lymphoma and nasopharyngeal carcinoma

EBV

16

Which DNA virus is associated with each of the following?
- gingivostomatitis

HSV-1

17

Which DNA virus is associated with each of the following?
- hides in sensory ganglia of S2 and S3

HSV-2

18

Which DNA virus is associated with each of the following?
- hides in trigeminal ganglia

HSV-1

19

Which DNA virus is associated with each of the following?
- hides in dorsal root ganglia

VZV

20

Which DNA virus is associated with each of the following?
- virus family of JC virus

polyomavirus

21

Which DNA virus is associated with each of the following?
- Downey cells

EBV

22

Which DNA virus is associated with each of the following?
- PML

JC virus (part of polyomavirus)

23

Which DNA virus is associated with each of the following?
- oral hairy leukoplakia

EBV

24

Which DNA virus is associated with each of the following?
- multinucleate giant cells on Tzanck test

HSV 1, 2, VZV

25

Which DNA virus is associated with each of the following?
- only DNA virus that is not double stranded

parvovirus

26

Which DNA virus is associated with each of the following?
- roseola

6th disease (HHV-6)

27

Which DNA virus is associated with each of the following?
- heterophile-negative mononucleosis

CMV

28

A 45 yo man with squamous cell carcinoma of the penis had exposure to which virus?

HPV

29

A 20 yo collage student presents with LAD, fever, and HSM. His serum agglutinates sheep red blood cells. What cell type is infection?

EBV virus --> infects B cells

30

What is the number one cause of fatal infantile gastroenteritis?

rotavirus