MSK Midterm Flashcards
Where can you find embryonic connective tissue?
umbilical cord, pulp of teeth
embryonic CT is rich in undifferentiated mesenchymal stem cells, extracellular matrix, and sometimes collagen or reticular fiber. what is CT in the umbilical cord called?
wharton’s jelly
embryonic CT is rich in undifferentiated mesenchymal stem cells can differentiate into what kinds of tissue?
any CT (adipose, cartilage, endothelium, osteocyte)
where do we find loose (areolar) CT?
mucosa and submucosa, deep to epithelium (surround vessels in tunica adventitia and nerves)
what are the extracellular components of areolar CT?
collagen and elastic fibers, ground substance
what are the cellular components of areolar CT?
mast cells, fibroblasts, macrophages
where in the body do we find dense regular CT?
tendon, ligament, cornea, fascia
fascia is made of what type of CT?
dense regular
where do we find dense irregular CT?
dermis and GI submucosa
what is the most common extracellular component of dense irregular CT?
collagen
what are the 2 kinds of dense irregular CT?
reticular and elastic
what type of cell is responsible for producing collagen, elastin, and reticular fiber as well as proteoglycans and glycoproteins for CT?
fibroblast
where do we find reticular CT? (dense irregular)
lymphatic tissue
where do we find elastic CT) (dense irregular with discontinuous lamellae around the lumen)
walls of large vessels and ligaments
what type of cell makes elastic fiber? (its made of elastin + fibrillin)
smooth muscle, fibroblast, chondroblast
this type of tissue is used as energy reserve and is unilocular
white fat (adipocytes)
this type of tissue is used to dissipate energy and is multilocular
brown fat (adipocytes)
which type of fat is rich in mitochondria and has numerous lipid deposits
brown fat
adipocytes are a modified form of what cell type that has used vacuole for lipid storage pushing all other cellular contents to the periphery?
modified fibroblast
this CT cell is spindle shaped with an oval nucleus
fibroblast
this is a 3 chain fibrous protein wound into a triple helix that is coiled for tensile strength
collagen
Where do you find Type I collagen? What are characteristics of the fibrils?
bone, tendon, dentin
banded fiber for tensile strength
Where do you find Type II collagen? What are characteristics of the fibrils?
hyaline and elastic cartilage
thinner fibrils
Where do you find Type III collagen? What are characteristics of the fibrils?
reticular lamina of the basement membrane
reticular fibrils