Nocardia Asteroides Flashcards Preview

Pulmonary Micro > Nocardia Asteroides > Flashcards

Flashcards in Nocardia Asteroides Deck (14):
1

What it look like?

G+ bacilli w/ branching coccobacillary hyphae. Saprophytic.

2

Aerobic or anaerobic?

Aerobic actinomycetes

3

Where it be?

Normal flora of soil + H2O

4

Why do they stain weakly acid fast?

Have short mycolic acid chains

5

Catalase and superoxide dismutase for what?

Tells PMNs and macrophages to fuck off

6

Cord factor does what?

Prevents phagolysosome fusion

7

Transmission?

Inhaled or soil infects skin wound. NO person-person or nosocomial.

8

Common in which patients?

With underlying debilitations. Opportunistic pathogen.

9

Disease?

Inhalation then grows in lungs forming lung abscesses. Can become systemic: infection/abscess in brain, blood, heart.

10

Diagnosis?

Smear/culture on BCYE. G stain. AF stain to confirm.

11

Treatment?

Sulfas.

12

How long do you treat an immunocompetent pt?

6-12 mos

13

How long do you treat an ICP?

12+ mos

14

What if no response to sulfas?

sulfa + ceftriaxone + amikacin regimen