(OLD) IASM 28: Connective Tissues

Question 1

Which germ layer is connective tissue originated?

Answer 1

Mesoderm

Question 2

Are there junctions between connective tissues?

Answer 2

No.

Question 3

What are the three types of connective tissues?

Answer 3

Connective Tissue Proper
Specialized Connective Tissues
Embryonic Connective Tissues

Question 4

What is included in the connective tissue proper?

Name 4

Answer 4

Lamina Propria
Dermis of Skin
Tendon
Ligaments

Question 5

What are in the specialized connective tissues?

Name 3

Answer 5

Cartilage and bone
Blood and haematopoietic tissues
Adipose tissues

Question 6

What are in the embryonic connective tissues

Name 2

Answer 6

Mesenchyme

Mucous connective tissue

Question 7

Proteoglycan molecules are highly charged. What is the function of this?

Answer 7

Holding lots of water

Question 8

what are functions of the connective tissues in the body?

Name 4

Answer 8

Supports epithelial tissue
Connect tissues or organs
Protection by physical barrier formation
Tissue repair
Regulation of behaviour of cells by the extracellular matrix

Question 9

Which type of collagen is the most abundant in human body?

Answer 9

Type I

Question 10

where is the type I collagen in human body

Name 4

Answer 10

tendon
ligament
skin
bone

Question 11

Which two things does a tendon connect

Answer 11

Muscle

Bone

Question 12

What is tropocollagen made up of

Components of the 3 chains of the triple helix

Answer 12

Alpha 1
Alpha 1
Alpha 2
Forming a triple helix

Question 13

What amino acids are tropocollagen abundant in

Name 3

Answer 13

Glycine
Proline
Hydroxyproline

Question 14

What cells contain type I collagen

Name 2

Answer 14

Fibroblasts

Osteoblasts

Question 15

Where is type I collagen located in the body?

Name 4

Answer 15

Tendon
Ligament
Dermis of skin
Bones

Question 16

What cell contain type II collagen

Answer 16

Chondroblasts

Question 17

Where is type II collagen found in body

Answer 17

Hyaline cartilage

Question 18

what cell contain type III collagen

Answer 18

Fibroblasts

Question 19

Where is type II collagen located in the body

Answer 19

Reticular fiber

Question 20

What cell contain type IV collagen

Answer 20

Epithelial cells

Question 21

Where is type IV collagen in the body

Answer 21

Basal lamina

Question 22

What is the function of reticular fibre

Answer 22

Form extensive network to support soft organs

Lymph node, spleen, red bone marrow, liver

Question 23

Is reticular fibre visible under Hematoxylin and Eosin staining

Answer 23

No

Question 24

Is reticular fibre visible under silver stain

Answer 24

Yes

Question 25

What term is called for things visible by silver stain

Answer 25

Argyrophilic

Question 26

What does PAS stain usually do

Answer 26

Stain polysaccharides

Question 27

Is reticular fibre PAS positive or negative? and Why?

Answer 27

Positive | High content of glycoproteins

Question 28

What is the structure of elastic fibres?

Answer 28

Amorphous core of elastin Surrounded by microfibrils/ fibrillin With cross-links between elastin molecules

Question 29

Is elastic fibre stained by H&E stain

Answer 29

No

Question 30

where are the elastic fibres located in the body | Name 3

Answer 30

Loose connective tissue (Loose network) aorta walls Ligamentum flavum in vertebral column

Question 31

What are the types of connective tissues? | Name 3

Answer 31

Loose/ areolar connective tissue Dense irregular connective tissue Dense regular connective tissue

Question 32

Where are the loose/ areolar connective tissue | Name 3

Answer 32

Lamina propria Mesentery Wharton's jelly

Question 33

where is lamina propria in the body

Answer 33

digestive or respiratory tract

Question 34

where is mesentery in the body

Answer 34

GI tract

Question 35

where is Wharton's jelly in the body

Answer 35

Umbilical cord

Question 36

Where is the dense irregular connective tissue

Answer 36

Dermis of skin

Question 37

Where is dense regular connective tissue | Name 3

Answer 37

Tendon ligament Aponeurosis (attaching muscle to bone)

Question 38

when active, called fibroblasts. | What is it called when it is quiescent?

Answer 38

Fibrocyte

Question 39

What is the function of the fibroblast | Name 5

Answer 39

``` Synthesize fibrous component Synthesize ground substance Response to tissue damage Synthesize new extracellular matrix Formation of scar tissue during wound healing ```

Question 40

Is macrophage specific or non-specific response

Answer 40

Non-specific

Question 41

Macrophages contain _______ for digestion

Answer 41

Lysosomes

Question 42

what are macrophages derived from?

Answer 42

Monocytes

Question 43

what is epitope?

Answer 43

small copy of digested antigen

Question 44

what is used to digest antigen in macrophage?

Answer 44

Lysosome

Question 45

What is used to present the epitope to the T-cell receptor

Answer 45

MHC II Protein

Question 46

are plasma cells basophilic? why?

Answer 46

Yes | There are a lot of rough endoplasmic reticulum

Question 47

What are the two types of adipose tissues

Answer 47

Multilocular adipocyte | Unilocular adipocyte

Question 48

what is the characteristic of unilocular adipocytes

Answer 48

Single large fat droplets

Question 49

what are characteristics of multilocular adipocytes | Name 2

Answer 49

Brownish colour: More blood vessels and mitochondria

Question 50

Multilocular adipose tissues are greatly reduced in _________ and more in _________

Answer 50

Adults; infants

Question 51

What type of cell is included in the cellular component of the connective tissues?

Answer 51

Immune Defence Cells

Question 52

What is included in non-cellular component of connective tissue? Fibrous Component---? Ground Substance----?

Answer 52

Fibrous component: Collagen Reticular Fiber Elastic Fiber Ground Substance: (Form gel-like matrix) Proteoglycan (Core protein + GAG) Glycoproteins