Oogenesis and Spermatogenesis Flashcards Preview

Endocrinology > Oogenesis and Spermatogenesis > Flashcards

Flashcards in Oogenesis and Spermatogenesis Deck (29):
1

When does oogenesis cease?

Menopause

2

Earliest recognisable germinal cell
Capable of mitosis
Migrate to genital ridge by week 6 of embryo development

Primordial germ cell

3

Completion of last pre-meitoic division forms what?

Oocytes

4

Presence of what signifies sperm entry and the completion of 2nd meiotic division?

2 polar bodies

5

In which phase does the egg mature and become ready for ovulation

Follicular phase

6

What signals the end of the follicular phase?

Ovulation

7

Which phase induces preparation of reproductive tract for pregnancy?
(if fertilisation occurs)

Luteal phase

8

The primary oocyte is surrounded by a layer of which type of cell?

Granulosa cells
-This is called the primary follicle

9

What helps the follicle to differentiate?

Hormonal influence

10

What happens to follicular cells left behind after ovulation?

They undergo luteinisation and transform into the corpus luteum

11

Which hormone is essential for preparation of uterine lining for implantation?

Progesterone (secreted in luteal phase)

12

How many days does the corpus luteum grow for?

8-9 days
(if no fertilisation has occured, it wil survive no longer than 14 days after ovulation)

13

What signals the start of a new follicular phase?

Degeneration of the corpus luteum

14

Which hormone stimulates secretion of oestradiol and ovulation?

FSH and LH

15

Which hormone stimulates follicle maturation, ovulation and development of corpeus luteum?

LH

16

These cells produce androgen which is converted by the granulosa to oestradiol

Theca cells

17

What does oestradiol do to the endometrium and cervical mucus?

Thickens endometrium and thins cervical mucus

18

Which hormone supresses FSH production

Oestrogen

19

Granulosa in the dominant follicle expresses what receptor?

LH receptor

20

High levels of what hormone at mid cycle cause hypothalamus to release GnRH?

Oestrogen
-causes FSH and LH surge from anterior pituitary

21

When does the follicular fluid and number of granulosa increase?

Ovulation

22

When does the cumulus oophorus loosen?

Ovulation

23

What does the corpeus luteum degenerate into?

Forms the corpus albicans

(if there is no hCG production by 12 days the corpus luteum degenerates etc...)

24

Which hormone maintains the corpus luteum?

hCG
Produces progesterone to support pregnancy and suppress ovulation

-Around 6 weeks the placenta takes over this role and the corpus luteum degenerates forming the corpus albicans

25

Hormone that stimulates testosterone secretion?

LH
(testosterone decreases release of GnRH and LH)

26

Which hormones stimulate spermatogenesis?

FSH and testosterone

27

Which hormone decreases secretion of FHS?

Inhibin

28

What do sertoli cell produce?

ABG (androgen binding globulin)
and Inhibin

(sertoli cells found in seminiferous tubule)

29

When is surgical sperm aspiration indicated?

Azoospermia