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Flashcards in Pregnancy again ... Deck (27):
1

Hormone produced in follicle growth?

Oestradiol

2

Hormone produced in fertilised ovum?

HCG

3

Hormone produced in corpus luteum?

Progesterone

4

Human placental lactogen
Placental progesterone
Placental oestrogen produced by what?

Placenta

5

Progesterones and hPL lead to what resistance in mother?

Insulin resistance

6

When does gestational diabetes present?

After 28 weeks

7

CNS defects in diabetes

Anencephaly, Spina bifida

8

Skeletal abnormalities in GD

Caudal regression syndrome

9

Genital and GI abnormalities in GD?

Ureteric duplication

10

Which makor growth factor is produced by foetus in the third trimester?

Insulin

11

What defines macrosomia?

BW>4kg

12

Supplement you give to diabetics in pregnancy?

Folic acid 5mg

13

Why do you give regular eye checks in pregnant diabetics?

Accelerated retinopathy

14

Which drugs should you avoid in pregnant diabetics?

ACEi's and statins

15

How would you control blood pressure in pregnant diabetics?

Labetalol, nifedipine, methyldopa

16

Blood sugar aims? (pre-meal and post meal?)

pre-meal <7-8 mmol/l

17

How do you maintain good blood glucose during labour?

IV insulin and IV dextrose

18

Treatment for MODY?

Glibenclamide!!

19

When should you carry out a post natal GTT?

6 week post natal GTT to ensure resolution

20

How often should you carry out fasting glucose checks after someone with gestational diabetes has had a baby etc?

Annual fasting glucose

21

hCG in hyperemesis gravidarum?

hCG HIGH
50-60% have abnormal TSH/fT4

22

Hypothyroidism in pregnancy, how often should you check TFT's?

Check TFTs montly for firs 20 weeks then 2 monthly until term

23

TSH aim for hypothyroidism in pregnancy?

Aim for TSH < 3mU/L

24

Untreated hypothyroidism risks in pregnancy?

Increased abortion, preeclampsia, abruption, postpartum haemorrhage, preterm labour,
Foetal neuropsychological development

25

Gestational hCG-associated Thyrotoxicosis

Hyperemesis gravidarum --> increased hCG, decreases TSH
Resolves by 20 weeks gestation
Only treat if persists >20 weeks

26

Hyperthyroid management in pregnancy?

beta blockers in early pregnancy
Propylthiouracil in 1st trimester
Carbimazole in 2nd/3rd trimester

27

Risks of hyperthyroidism in pregnancy?

Stillbirth
Spontaneous miscarriage
Thyroid crisis during labour
Neonatal thyrotoxicosis