Flashcards in Pituitary and Adrenal Gland Deck (24):
Describe the tissue of the posterior pituitary gland
It is an extension of neural tissue consisting of modified glial cells and axonal processes
What do somatotrophs secrete?
What do mammotrophs secrete?
Name 3 types of basophil and what they produce
What do corticotrophs produce?
What do thyrotrophs produce?
What do gonadotrophs produce?
Which part of the thyroid gland contains non-myelinated axons of neurosecretory neurons?
Posterior gland of the pituitary
Hypopituitarism caused by ischemic necrosis due to blood loss and hypovolemic shock during and after childbirth
What could a tumour extending into the sella cause?
Inflammatory conditions (e.g. sarcoid) and the pituitary gland?
Could cause hypothyroidism
Sudden Haemorrhage into gland
Tumours extending into sella
Inflammatory conditions (Sarcoidosis)
Which gland does SIADH affect?
Syndrome of inappropriate ADH secretion affects the posterior pituitary (lel, posterior is in charge of ADH secretion so thats obvious lol)
Multiple endocrine neoplasia (Werner syndrome)
Addison's Disease Typical Presentation
Malaise, tiredness, poor appetite, weight loss
CRAVING FOR SALTY FOOD
Low BP, postural hypotension
Most common cause of Addison's disease?
Symptoms specific to women in addisons?
Loss of body hair and periods may stop
What other disease may be associated with Addison's disease?
Type 1 diabetes, autoimmune thyroid disease, pernicious anemia
Why might patients with addisons become hypoglycaemic?
Steroids make you more insulin resistant, in addisons you aren't producing sufficient steroids and so you become more insulin sensitive
Diagnosis of Adrenal Insufficiency
-Low sodium, high potassium, hypoglycaemia
-Short Synachten Test (>250, >480)
-ACTH levels will be high
-Renin will be massively increased, Aldosterone will be decreased
Most common type of pituitary adenoma?
Symptoms of prolactinoma?
Infertility, lack of libido, amenorrhoea
What causes levels of insulin like growth factors to rise?
Symptoms of a growth hormone secreting functional adenoma?
Growth of bone, cartilage and connective tissue
Gigantism or acromegaly