Oral path Chapter 7 viral infections Flashcards

(58 cards)

1
Q

What is HHV-3?

A

-Varicella-zoster virus (VZV)

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2
Q

What is HHV-4?

A

-Epstein-Barr virus

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3
Q

What is HHV-5?

A

-Cytomegalovirus

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4
Q

What is HHV-8?

A

-Kaposi’s sarcoma

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5
Q

What is the most common disease resulting from EBV exposure?

A

-Infectious mononucleosis

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6
Q

What are some other lesions/diseases that demonstrate EBV?

A
  • Oral hairy leukoplakia
  • Lymphomas
  • Lymphoproliferative disorders (African’s Burkitt’s lymphoma
  • Nasopharyngeal carcinoma
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7
Q

How is EBV infections spread?

A

-Intimate contact

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8
Q

What does a Diagnosis of EBV need to have?

A

-Presence of Paul-Bunnel heterophil antibodies

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9
Q

For the classical infection of mononucleosis what are some things to look for?

A
  • Fatigue
  • Malaise
  • Anorexia
  • Fever up to 104 and last 2 weeks
  • lymphadenopathy (tonsilar hyperplasia/cervical enlargement)
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10
Q

What oral lesions are associated with mono (EBV)?

A
  • Oropharyngeal tonsillar enlargement
  • Petechiae on hard palate
  • Necrotizing ulcerative gingivitis
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11
Q

What are enteroviruses classified into?

A
  • Echoviruses
  • Coxsackievirus
  • Poliovirus
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12
Q

What are three important diseases caused by coxsackievirus?

A
  • Herpangina
  • Hand-foot-and mouth disease
  • Acute lymphonodular pharyngitis
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13
Q

What type of signs and symptoms are associated with herpangina?

A
  • Skin rash
  • Sore throat
  • Fever
  • Oral lesions in the posterior mouth
  • Begin as red macules
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14
Q

What signs and symptoms are associated with hand foot and mouth disease?

A
  • Skin rash
  • oral lesions associated with flu like symptoms
  • Oral lesions arise first (larger than herpangia)
  • Affect buccal mucosa, labial mucosa, and tongue most commonly
  • Cutaneous lesions on borders of palms and soles
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15
Q

What signs and symptoms are associated with acute lymphonodular pharyngitis?

A
  • 1-5 yellow to dark pink nodules on the soft palate
  • Represent hyperplastic lymphoid aggregates
  • Fever
  • Sore throat
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16
Q

What causes Rubeola (measles)?

A

-Paramyxovirus

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17
Q

When do most cases of Rubeola arise?

A

-Winter

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18
Q

How is measles spread?

A

-Respiratory droplets

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19
Q

How many stages are there for measles?

A

3 stages for 3 days each

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20
Q

What occurs in the first stage of measles?

A
  • Coryza (runny nose)
  • Cough
  • Conjunctivitis
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21
Q

What stage of measles has the most distinctive oral manifestations, and what are these manifestations called?

A
  • First stage

- Koplik’s spots

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22
Q

What are Koplik’s spots?

A
  • Represent foci of epithelial necrosis
  • Pathognomonic
  • Multiple areas of mucosal erythema with numerous small, blue-white macules
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23
Q

What occurs in the second stage of measles?

A
  • Fever continues
  • Koplik’s spots fade
  • Maculopapular & erythematous rash begins (Starts with the face first)
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24
Q

What occurs in the third stage of measles?

A
  • Fever ends

- Rash fades

25
What causes Rubella (german measles)?
-Togavirus
26
What is congenital rubella syndrome?
- Deafness - Heart disease - Cataracts
27
What can rubella cause?
-Birth defects
28
What oral lesions is associated with rubella?
-Forchheimer's sign (small, discrete, dark-red papules on the palate)
29
What is considered 9 day measles?
Rubeloa
30
What is considered 3 day measles?
-Rubella
31
What is a disease of exocrine glands?
-Mumps
32
What exocrine glands are the best known sites of involvement for mumps?
-Salivary glands
33
What do the involved glands of mumps exhibit?
- Edema | - Lymphocytic infiltration
34
What is the route of transmission for HIV?
- Sexual contact - Parenteral exposure to blood - Transmission from mother to fetus
35
What is the target cell for HIV?
-CD4 + Helper T lymphocyte
36
What oral manifestations are strongly associated with HIV infections?
- Candidiasis - Hairy leukoplakia (EBV) (white lesions bilateral on side of tongue) - Kapsi's sarcoma - Non-Hodgkin's lymphoma - Periodontal diseases
37
What do you do for treatment with someone with HIV and candidiasis?
-Topical clotrimazole
38
What is the most common EBV related lesions in AIDS pts?
-Oral Hairy leukoplakia
39
What is characteristic of oral hairy leukoplakia?
-Found bilateral on lateral tongue, white plaque that doesn't wipe off
40
What is a multifocal neoplasm of vascular endothelial cell origin?
-Kaposi's sarcoma
41
What are the most common sites of Kaposi's sarcoma?
- Hard palate - Gingiva - Tongue
42
HSV-1 is found where?
-Above the waste
43
Where is HSV-2 found?
-Below the waste
44
How do shingles present?
-Unilateral from dermatone
45
What does HHV-3 reside?
-Dorsal root ganglion
46
Where does HHV-1 reside?
-Trigeminal ganglion
47
What is a herpetic whitlow?
-Herpetic paronychia is infection of the thumb or fingers
48
What is the term for a primary herpes of HSV-1?
-Acute herpetic gingivostomatitis
49
Where do recurrent herpes simplex happen intraoral lesions?
-On keratinized bound mucosa (palate, attached gingiva)
50
What is the most common site of recurrence for HSV-1?
-Vermilion border
51
If you are younger than 18 what is the name of primary HSV-1 infection?
-Gingivostomatitis
52
If you are older than 19 what is the name of primary HSV-1 infections?
-Pharyngotonsillitis
53
What are the histopathologic features of HSV?
- Multinucleation - Ballooning degenerations - Tzanck cells
54
If you have shingles impacting the tip of the nose is that a medical emergency?
-Yes can lead to blindness
55
What is Ramsay Hunt Syndrome?
- Cutaneous lesions of the external auditory canal - Involvement of ipsilateral face (facial paralysis, hearing defects, vertigo) - VZV
56
What is another name for mumps?
-Epidemic parotitis
57
What is Forchheimers sign associated with?
-Rubella
58
What is swollen testicles associated with?
-Mumps