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Oral Pathology 2020 > Chapter 16 lecture 2 > Flashcards

Chapter 16 lecture 2 Flashcards

1
Q

What does cicatrix means?

A

-Scar

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2
Q

What is another term for mucous membrane pemphigoid?

A

-Cicatrical pemphigoid

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3
Q

T/F Mucous membrane pemphigoid is twice as common as pemphigus

A

True

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4
Q

If you see an intraoral blood blister what should you be thinking about?

A

-mucous membrane pemphigoid

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5
Q

What is the most significant complication in mucous membrane pemphigoid?

A

-Ocular involvement

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6
Q

If mucous membrane pemphigoid progresses what happens to the conjunctiva?

A
  • Inflamed

- Eroded

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7
Q

What are adhesions from mucous membrane pemphigoid from the conjunctiva becoming inflamed and eroded which leads to scarring?

A

Symblepharons

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8
Q

If scarring in mucous membrane pemphigoid occurs and turn the eyelids inward what is that called?

A

-Entropion

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9
Q

T/F The cornea can produce keratin as a protective mechanism in pemphigoid

A

True

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10
Q

What type of split do you see in pemphigoid?

A

-Subepithelial split

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11
Q

What do you see in a direct immunofluorescence in pemphigoid?

A
  • C3

- IgG (both along basement membrane)

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12
Q

What is Erythema Multiforme?

A

-Blistering ulcerative mucocutaneous condition of uncertain etiopathogenesis

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13
Q

What infections can cause erythema multiforme?

A
  • Herpes simplex (1)

- Mycoplasma pneumoniae

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14
Q

What medications can cause Erythema multiforme?

A
  • Antibiotics

- Analgesics

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15
Q

What is Erythema mulftiforme (EM) major aka?

A

-Steven’s Johnson syndrome

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16
Q

What three things do you see on the spectrum of EM?

A
  • EM minor
  • EM major
  • Txoic epidermal necrolysis
17
Q

What is toxic epidermal necrolysis aka?

A

-Lyell’s disease

18
Q

What are the prodromal symptoms of EM?

A
  • Fever
  • Headache
  • Cough
  • Sore throat
19
Q

How long does EM last for?

A

2-6 weeks with 20% having recurrent episodes

20
Q

What do early lesions of EM look like?

A
  • Flat
  • Round
  • Red
21
Q

A highly characteristic skin lesion with EM are called what and what are they?

A
  • Target lesions

- Concentric circular erythematous rings resembling a target or bull’s eye

22
Q

T/F With EM pts may become dehydrated due to an inability to ingest liquids

A

True

23
Q

To make the diagnosis of Steven-Johnson syndrome what must there be involved?

A
  • Skin
  • Oral mucosa
  • Ocular or genital involvement
24
Q

What is the most sever form of EM?

A

Toxic epidermal necrolysis

25
Q

What is toxic epidermal necrolysis almost always triggered by ?

A

-Drug

26
Q

What is used in the management of os EM minor and major?

A

Steroids

27
Q

What is lichen planus?

A

-Common chronic dermatologic disease that can affect the oral mucosa

28
Q

What might cause lichen planus?

A
  • Medications
  • Amalgam
  • etc
29
Q

What are the 4 skin lesion Ps in lichen planus?

A
  • Purple
  • Pruritus
  • Polygonal
  • Papules
30
Q

In lichen planus the skin papules will also have a thin, lacelike network of wheet lines termed what?

A

-Wickham’s striae

31
Q

What are the two forms of lichen planus?

A
  • Reticular

- Erosive

32
Q

Which form of lichen planus is more common?

A

-Reticular

33
Q

Which type of lichen planus is asymptomatic?

A

-Lichen planus

34
Q

T/F Lichen planus is only found unilateral

A

False

-It is found bilaterally

35
Q

What type of lichen planus is symptomatic?

A

-Erosive

36
Q

What does erosive lichen planus look like?

A
  • Atrophic

- Erythematous areas with a central ulcerations

37
Q

If erosive lichen planus is confined to the gingiva what is it termed?

A

-Desquamative gingivitis

38
Q

What can induce lichen planus lesions?

A
  • Stress
  • Trauma
  • Advil
  • Yeast

Oral Pathology 2020 (38 decks)

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