P15 - Leukocytes Part 5

Question 1

morphologic changes associated with inflammatory disease (4)

Answer 1

• toxic neutrophils
• giant neutrophils
• hypersegmented neutrophils
• reactive lymphocytes

Question 2

organisms in leukocytes (4)

Answer 2

• ehrlichial (anaplasmal) organisms
• histoplasma capsulatum
• hepatozoon americanum
• hepatozoon canis

Question 3

ehrlichial (anaplasmal) organisms identifying features (3)

Answer 3

• mulberry-type morula
• light-grey to blue-grey staining
• one or multiple morulae

Question 4

histoplasma capsulatum identifying features

Answer 4

• size and shape - round to oval
• cell wall is nonstaining
• internal “nuclear” staining
• bud

Question 5

stages of canine lymphoma

Answer 5

• I -> single LN or single organ
• II -> many LN’s in region
• III -> generalized lymphadenopathy
• IV -> liver &/or spleen involved
• V -> marrow, CNS, or other extranodal sites

Question 6

acute leukemia

Answer 6

• blastic (less differentiated) cell

- express CD34

Question 7

chronic leukemia

Answer 7

• relatively well-differentiated cells

Question 8

toxic neutrophils characteristics (4)

Answer 8

• foamy cytoplasms
• diffuse cytoplasmic basophilia
• Dohl bodies
• giant neutrophils

Question 9

clinical lymphoproliferative disease

Answer 9

• lymphoma - may spread to blood and/or marrow

- myeloma

Question 10

clinical myeloproliferative disease

Answer 10

• acute and chronic leukemias (blood &/or marrow)