Flashcards in Pancreatic Disorders Deck (21)
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1
stimulates the release of bicarbonate and water
secretin
2
acts directly and through vagal afferents to stimulate pancreatic acinar cells to release digestive proenzymes.
CCK
3
Common cause of acute pancreatitis in men and women
women-gallstones. men-alcohol
4
Clinical manifestations include: persistent, severe epigastric pain
or RUQ pain may be steady or colicky
N & V. band like radiation of pain to back
acute pancreatitis
5
Patient may have dyspnea, tachycardia, fever, ecchymotic discoloration observed in periumbilical region or along plank, shock/coma
acute pancreatitis
6
Lab tests that should be ordered to assess pancreatitis
serum amylase, lipase, CRP
7
most important test for diagnosis acute pancreatitis & intraabdominal complications and assessment of severity; ideally should have oral contrast and IV contrast
CT scan
8
Progressive inflammatory changes result in permanent structural damage to the pancreas, leading to impairment of exocrine & endocrine function
chronic pancreatitis
9
Most common cause of chronic pancreatitis
alcohol abuse
10
Treatment of acute pancreatitis without complications
hospitalize, fluids, NPO, bedrest
11
Clinical manifestations include: chronic abdominal pain, pancreatic insufficiency, fat malabsorption, pancreatic DM
chronic pancreatitis
12
Why are amylase and lipase usually normal in chronic pancreatitis?
because pancreas fibrotic resulting in decreased abundance of these enzymes within the pancreas
13
Imaging may show calcifications, ductal dilation, enlargement of pancrease, pseudocysts
chronic pancreatitis
14
Pharm treatment for chronic pancreatitis
NSAIDs, amitriptyine, opiates
15
Dietary recommendations for chronic pancreatitis
no ETOH/smoking, small low fat meals w/pancreatic enzyme supplements and H2 blockers or PPIs
16
Surgical treatment for chronic pancreatitis if medical and dietary therapy has failed
decompression of main pancreatic duct/psuedocyst, resection of part of the pancreas, denervation procedures
17
Classic manifestation of pancreatic cancer
painless jaundice w/weight loss
18
What is the L. supraclavicular node also called?
Virchow's node
19
Survival rate for stage IV pancreatic cancer
50% have limited survival of 3-6 months
20
Imaging: US/CT shows pancreatic mass, dilated bile ducts, liver mets
Pancreatic cancer
21
