Pancreatic Disorders Flashcards

1
Q

stimulates the release of bicarbonate and water

A

secretin

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2
Q

acts directly and through vagal afferents to stimulate pancreatic acinar cells to release digestive proenzymes.

A

CCK

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3
Q

Common cause of acute pancreatitis in men and women

A

women-gallstones. men-alcohol

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4
Q

Clinical manifestations include: persistent, severe epigastric pain
or RUQ pain may be steady or colicky
N & V. band like radiation of pain to back

A

acute pancreatitis

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5
Q

Patient may have dyspnea, tachycardia, fever, ecchymotic discoloration observed in periumbilical region or along plank, shock/coma

A

acute pancreatitis

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6
Q

Lab tests that should be ordered to assess pancreatitis

A

serum amylase, lipase, CRP

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7
Q

most important test for diagnosis acute pancreatitis & intraabdominal complications and assessment of severity; ideally should have oral contrast and IV contrast

A

CT scan

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8
Q

Progressive inflammatory changes result in permanent structural damage to the pancreas, leading to impairment of exocrine & endocrine function

A

chronic pancreatitis

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9
Q

Most common cause of chronic pancreatitis

A

alcohol abuse

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10
Q

Treatment of acute pancreatitis without complications

A

hospitalize, fluids, NPO, bedrest

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11
Q

Clinical manifestations include: chronic abdominal pain, pancreatic insufficiency, fat malabsorption, pancreatic DM

A

chronic pancreatitis

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12
Q

Why are amylase and lipase usually normal in chronic pancreatitis?

A

because pancreas fibrotic resulting in decreased abundance of these enzymes within the pancreas

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13
Q

Imaging may show calcifications, ductal dilation, enlargement of pancrease, pseudocysts

A

chronic pancreatitis

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14
Q

Pharm treatment for chronic pancreatitis

A

NSAIDs, amitriptyine, opiates

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15
Q

Dietary recommendations for chronic pancreatitis

A

no ETOH/smoking, small low fat meals w/pancreatic enzyme supplements and H2 blockers or PPIs

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16
Q

Surgical treatment for chronic pancreatitis if medical and dietary therapy has failed

A

decompression of main pancreatic duct/psuedocyst, resection of part of the pancreas, denervation procedures

17
Q

Classic manifestation of pancreatic cancer

A

painless jaundice w/weight loss

18
Q

What is the L. supraclavicular node also called?

A

Virchow’s node

19
Q

Survival rate for stage IV pancreatic cancer

A

50% have limited survival of 3-6 months

20
Q

Imaging: US/CT shows pancreatic mass, dilated bile ducts, liver mets

A

Pancreatic cancer

21
Q

Tumor marker for pancreatic cancer that can be used to assess response to treatment

A

CA 19.9