Pancreatic Disorders Flashcards Preview

Gastroenterology > Pancreatic Disorders > Flashcards

Flashcards in Pancreatic Disorders Deck (21):
1

stimulates the release of bicarbonate and water

secretin

2

acts directly and through vagal afferents to stimulate pancreatic acinar cells to release digestive proenzymes.

CCK

3

Common cause of acute pancreatitis in men and women

women-gallstones. men-alcohol

4

Clinical manifestations include: persistent, severe epigastric pain
or RUQ pain may be steady or colicky
N & V. band like radiation of pain to back

acute pancreatitis

5

Patient may have dyspnea, tachycardia, fever, ecchymotic discoloration observed in periumbilical region or along plank, shock/coma

acute pancreatitis

6

Lab tests that should be ordered to assess pancreatitis

serum amylase, lipase, CRP

7

most important test for diagnosis acute pancreatitis & intraabdominal complications and assessment of severity; ideally should have oral contrast and IV contrast

CT scan

8

Progressive inflammatory changes result in permanent structural damage to the pancreas, leading to impairment of exocrine & endocrine function

chronic pancreatitis

9

Most common cause of chronic pancreatitis

alcohol abuse

10

Treatment of acute pancreatitis without complications

hospitalize, fluids, NPO, bedrest

11

Clinical manifestations include: chronic abdominal pain, pancreatic insufficiency, fat malabsorption, pancreatic DM

chronic pancreatitis

12

Why are amylase and lipase usually normal in chronic pancreatitis?

because pancreas fibrotic resulting in decreased abundance of these enzymes within the pancreas

13

Imaging may show calcifications, ductal dilation, enlargement of pancrease, pseudocysts

chronic pancreatitis

14

Pharm treatment for chronic pancreatitis

NSAIDs, amitriptyine, opiates

15

Dietary recommendations for chronic pancreatitis

no ETOH/smoking, small low fat meals w/pancreatic enzyme supplements and H2 blockers or PPIs

16

Surgical treatment for chronic pancreatitis if medical and dietary therapy has failed

decompression of main pancreatic duct/psuedocyst, resection of part of the pancreas, denervation procedures

17

Classic manifestation of pancreatic cancer

painless jaundice w/weight loss

18

What is the L. supraclavicular node also called?

Virchow's node

19

Survival rate for stage IV pancreatic cancer

50% have limited survival of 3-6 months

20

Imaging: US/CT shows pancreatic mass, dilated bile ducts, liver mets

Pancreatic cancer

21

Tumor marker for pancreatic cancer that can be used to assess response to treatment

CA 19.9