Flashcards in Cirrhosis Deck (13)
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1
development of fibrosis of liver with formation of regenerative nodules; results in impairment of synthetic, metabolic and hemodynamic functions of the liver
cirrhosis
2
Gold standard for diagnosis of cirrhosis
biopsy
3
T/F Early fibrotic changes are reversible, as progression occurs the changes become irreversible
true
4
Levels fall as cirrhosis worsens
albumin
5
Levels rise as cirrhosis worsens
bilirubin
6
Why does prothrombin time increase with cirrhosis?
ability of cirrhotic liver to synthesize clotting factors diminishes
7
What happens to sodium levels when there is ascites and high levels of ADH?
hyponatremia
8
usually the first hematologic abnormality of cirrhosis; secondary to portal hypertension and attendant congestive splenomegaly
thrombocytopenia
9
Increased blood pressure in the portal vein due to increased resistance to the blood passing through the vessels in the liver
portal hypertension
10
Treatment of portal hypertension
remove ascitic fluid, portal shunts, liver transplant
11
Spectrum of potentially reversible neuropsychiatric abnormalities
hepatic encephalopathy
12
neurotoxin that precipitates hepatic encephalopathy
ammonia
13