Patho OSCE - Immunhistochemie Flashcards

1
Q

CD34

A

negativ: Leberzirrhose
positiv: HCC

Färbemuster: membranös

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2
Q

p16+

A

CIN3 bei Plattenepithel-Ca der Zervix

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3
Q

HER2/neu+

A

bei 30% der Mamma-Ca’s

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4
Q

HMB45+

A

Malignes Melanom

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5
Q

HMWCK-

A

Adeno-Ca Prostata (im gesunden Gewebe/PIN+)

Färbemuster: cytoplasmatisch

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6
Q

PLAP+

A

Seminom

Färbemuster: membranös, cytoplasmatisch

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7
Q

MLH1-

A

Colorektales Ca

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8
Q

E-Cadherin-

A

diffuses Magen-Ca

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9
Q

CD117 (c-KIT)+

A

GIST

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10
Q

Ki-67

A

positiv: parakortikale Hyperplasie LK, (Kleinzeller, kein Präparat), aggressives DLBCL
negativ: follikuläres Lymphom

Färbemuster: nukleär

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11
Q

CD30+

A

Hodgkin-Lymphom

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12
Q

bcl-2+

A

Follikuläres Lymphom (Ki-67-)

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13
Q

CD20+ und CD3-

A

aggressives DLBCL (Ki-67+)

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14
Q

P53+

A

seröses Ovarial-Ca (meistens)

Färbemuster: nukleär

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15
Q

P40+

A

Plattenepithel-Ca der Lunge

Färbemuster: nukleär

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16
Q

TTF1+

A

Adeno-Ca der Lunge

Färbemuster: nukleär

17
Q

Synaptophysin+

A

Kleinzeller (Ki-67 positiv)

Färbemuster: zytoplasmatisch