Pharm 1 Liner- Autonomics Flashcards Preview

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Flashcards in Pharm 1 Liner- Autonomics Deck (50):
1

Beta blockers with partial agonist activity, can bronchodilator and may have an advantage treating patients with asthma (2)

Pindolol, acebutolol

2

Indicated for symptomatic orthostatic hypotension

Midodrine

3

Antimuscarinic for prophylaxis of motion sickness

Scopolamine

4

Beta blockers effect on the heart in antianginal therapy (6)

Reduce heart rate, blood pressure, contractility, myocardial oxygen consumption, increase ejection time, and no change or increase end diastolic volume

5

Blocks alpha 1 and beta receptors and indicated for treatment of CHF

Labetalol and carvedilol

6

Its ability to vasoconstrict and increase blood pressure makes it useful as local decongestant and for the therapy of spinal shock (temporary maintenance of blood pressure)

Alpha 1 agonists

7

Treatment of myasthenia gravis and sometimes used prophylactically for organophosphate poisoning in chemical warfare

Pyridostigmine

8

Organophosphate, indicated for glaucoma but not used much clinically due to long duration of action

Echothiophate

9

Alpha 1a-selective blocker used for BPH

Tamsulosin

10

A non-selective beta blocker with alpha 1 blocking effect indicated for CHF

Carvedilol

11

Beta blockers are used for this type of angina attack

Classic (exertional) angina

12

Beta blockers should be used cautiously in (3)

Asthma (bronchospastic effects), diabetics (block signs of hypoglycemia), and peripheral vascular disease

13

Toxicity caused by this class of drugs is chars by DUMBELSS (diarrhea, urination, miosis, bronchoconstriction, excitation of skeletal muscle and CNS, lacrimation, salivation, sweating)

Cholinergic drugs

14

Indirect acting sympathomimetic, improves urinary continence in children and elderly with enuresis

Ephedrine

15

Short acting beta blocker that can be given parenterally, commonly used in hemodynamically unstable patients

Esmolol

16

Beta 1 agonist toxicity (2)

Sinus tachycardia and serious arrhythmia

17

Contraindications to use atropine (3)

Infants, closed angle glaucoma, prostatic hypertrophy

18

Its ability to increase heart rate makes it useful as adjunct therapy for acute herat failure and hypovolemia or septic shock

Beta 1 agonist

19

Muscarinic selective cholinomimetic used to diagnose asthma

Methacholine

20

Longer acting beta 2 agonist, indicated for prophylaxis of asthma

Slameterol

21

Alpha agonist indicated for nasal congestion, hypotension, and mydriasis induction

Phenylephrine

22

Indirect acting sympathomimetic, reuptake inhibitor, commonly abused, indicated for attention deficit disorder and weight reduction

Methaphetamine

23

Insecticide organophosphate

Malathion, parathion

24

Beta agonist used in acute CHF

Dobutamine and dopamine

25

Drug of choice for anaphylactic shock

Epinephrine

26

Anti muscarinic that produces mydriasis and cycloplegia

Atropine and anti-muscarinics

27

Irreversible, non-selective alpha-blocker indicated for pheochromocytoma

Phenoxybenzamine

28

Short acting beta 2 agonist, drug of choice for acute asthma

Albuterol

29

Selective beta 1 receptor blockers useful for treating cardiac conditions in patients with asthma (5)

Acebutolol, betaxolol, esmolol, atenolol, metoprolol (A BEAM)

30

Pneumonic for beta receptors

You have 1 heart (beta 1) and 2 lungs (beta 2)

31

This agent has greater affinity for muscarinic receptors and used for postoperative and neurogenic ileus and urinary retention

Bethanechol

32

Atropine fever is the most dangerous effect and can be lethal in this population group

Infants

33

Selective alpha 1 blocker used for HTN, BPH, may cause first dose orthostatic Hypotension (3)

Prazosin, terazosin, doxazosin

34

Alpha 1 agonist toxicity

Hypertension

35

The most important cause of acute deaths in cholinesterase inhibitor toxicity

Respiratory failure

36

Beta 2 agonist adverse effect

Skeletal muscle tremor

37

Mechanism of action of atropine

Non-selective antimuscarinic

38

Beta 2 agonist used to suppress premature labor, but cardiac stimulatory effects may be hazardous to mother and fetus

Terbutaline

39

Reversible, non-selective alpha blocker indicated for pheochromocytoma

Phentolamine

40

Antimuscarinic that treats Parkinsonism and extrapyramidal disease

Benztropine

41

Alkaloid muscarinic that is very lipid soluble and used in glaucoma

Pilocarpine

42

Used in treatment of muscarinic symptoms in organophosphate overdose

Atropine

43

Cholinesterase inhibitor, intermediate duration of action, used off label for postoperative paralytic ileus and urinary retention

Neostigmine

44

Antimuscarinic indicated for overactive bladder muscle dysfunction

Oxybutynin

45

Side effects of beta blockers

Bradycardia, AB block, impotence, dyslipidemia, exacerbation of COPD

46

Cholinesterase inhibitor, short duration of action, used in diagnosis of myasthenia gravis

Edrophonium

47

Antimuscarinic that causes bronchodilation in asthma and COPD (2)

Ipatropium, tiotropium

48

Non-selective beta blocker that lacks local anesthetic activity, indicated for glaucoma

Timolol

49

Muscarinic used to treat dry mouth in Sjögren's syndrome

Pilocarpine or cevimeline

50

Cholinesterase inhibitor, lipid soluble, indicated for atropine overdose and glaucoma

Physostigmine