Flashcards in Pharm 30 Treatment Questions Deck (15)
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1
What oral agent used to control type II diabetes has the following characteristic?Lactic acidosis (rare but worrisome)
Biguanide: metformin
2
What oral agent used to control type II diabetes has the following characteristic?Most common side effect is hypoglycemia
Sulfonylureas First generation: generally not used
Second generation: Glyburide, glimepiride and glipizide
3
What oral agent used to control type II diabetes has the following characteristic?Often used in combination with any of the other oral agents
Metforminbut many of these agents can be combined
4
What oral agent used to control type II diabetes has the following characteristic?Also help lower triglycerides and LDL cholesterol levels
Biguanides: Metformin
5
What oral agent used to control type II diabetes has the following characteristic?Not safe in settings of hepatic dysfunction or CHF
-Biguanides: metformin
-Glitazones/thiazolidinediones
6
What oral agent used to control type II diabetes has the following characteristic?Should not be used in patients with elevated serum creatinine
Biguanides: metformin (due to risk of lactic acidosis)
7
What oral agent used to control type II diabetes has the following characteristic?Should not be used in patients with liver cirrhosis, elevated serum creatinine or inflammatory bowel disease.
alpha- glucosidase inhibitors: acarbose and miglitol
8
What oral agent used to control type II diabetes has the following characteristic?Hepatic serum transaminase levels should be carefully monitored when using these agents.
-Biguanides: metformin
-Glitazones/thiazolidinediones
9
What oral agent used to control type II diabetes has the following characteristic?Not associated with weight gain, often used in overweight diabetics
Biguanide: metformin
10
What oral agent used to control type II diabetes has the following characteristic?Metabolized by liver; excellent choice in patients with renal disease
Gliazones/thiazolidinediones
11
What oral agent used to control type II diabetes has the following characteristic?Primarily effects postprandial hyperglycemia
alpha-glucosidase inhibitors: acarbose and miglitol
12
What oral agent used to control type II diabetes has the following characteristic?MOA: closes K channel on Beta cells causes depolarization and Ca influc and insulin release
Sulfonylureas: First gen and second gen (glyburide, glimepiride and glipizide)
13
What oral agent used to control type II diabetes has the following characteristic?MOA: inhibits alpha-glucosidase at intestinal brush border
alpha-glucosidase inhibitors: acarbose and miglitol
14
What oral agent used to control type II diabetes has the following characteristic?MOA: agonist at PPAR-gamma receptors and improves target cell response to insulin
Gliazone/thiazolidinediones: pioglitazone and rosglitazone
15
