Pharm: Bootcamp

Question 1

If a drug has less protein binding, how does that affect the drug?

Answer 1

Less duration of action

Question 2

IF a drug has more protein binding, how does that affect the drug?

Answer 2

Longer duration of action

Question 3

If a drug has a lower pKA, how does that affect the drug?

Answer 3

More rapid onset of action

Question 4

If a drug has a higher pKA, how does that affect the drug?

Answer 4

More slow onset of action

Question 5

What is the max recommended dose for Prilocaine?

Answer 5

600 mg

Question 6

What 2 things should be administered in case of methemoglobinemia?

Answer 6

Vitamin C and methylene blue

Question 7

Where in the brain does cocaine predominately exert its effect?

Answer 7

Nucleus accumbens

Question 8

If a pt has a candida infection after being on Abx, what should you do?

Answer 8

Remove source of infection, discontinue Abx, clomitrazole troche

Question 9

What med is used to treat Mucormycosis?

Answer 9

Amphotericin B

Question 10

What type of agent should be taken as a prophylactic for a pt about to begin chemo?

Answer 10

Antifungal like Nystatin

Question 11

What med inhibits fungal cytochrome P450 and inhibits cell membrane formation?

Answer 11

Fluconazole
-azoles

Question 12

Which of the following medical conditions requires antibiotic prophylaxis?
Tetralogy of Fallot
Calcific aortic stenosis
History of total joint replacement
Mitral Valve Prolapse

Answer 12

Tetralogy of Fallot

Question 13

Which of the following medical conditions requires antibiotic prophylaxis?

Answer 13

Inhibits synthesis of an integral part of hte fungal cell membrane

Question 14

What should be used to treat angular chelitis?

Answer 14

Nystatin and triamclione cream

Question 15

Which ion determines binding affinity of agonists and antagonists to the mu-opioid receptor?

Answer 15

Sodium

Question 16

Each of the following are appropriate mu-receptor agonists to provide analgesia for this patient EXCEPT one. Which is the EXCEPTION?
Nalbuphine
Hydrocodone
Tramadol
Codeine

Answer 16

Nalbuphine: mixed agonist/antagonist

Question 17

Which of the following can be a potential side effect of morphine?
Mydriasis
Pneumonia
HTN
Increased wakefulness

Answer 17

Pneumonia

Question 18

Codeine is the prodrug for what analgesic medication?

Answer 18

Morphine

Question 19

Codeine is ineffective in patients with which of the following comorbidities?
CHF
DM
Kidney failure
Liver failure

Answer 19

LIver failure

Question 20

All of the following are medicinal uses of marijuana targeting the cannabinoid receptors EXCEPT one. Which is the EXCEPTION?
REducing schiz episode
Decreasing N and V in chemo pts
Alleviating chronic pain
Decreasing muscle spasm during seizures

Answer 20

Reducing schiz episodes

Question 21

Each of the following is a possible symptom of the patient’s recreational drug use EXCEPT one. Which is the EXCEPTION?
Paranoia
Xerostomia
Bradycardia
Altered sense of time

Answer 21

Bradycardia

Question 22

___ drugs are contraindicated in pts with acute intermitten porphyria

Answer 22

Barbituates

Question 23

What med out of lorazepam, midazolam, diazepam, and triazolam would be best to give an axious adult for a 1 hour appt?

Answer 23

Triazolam: short acting

Question 24

What is the MOA of carbamazepine?

Answer 24

Blocks Na channels

Question 25

Each of the following is a side effect of the patient’s medication: methylphenidate EXCEPT one. Which is the EXCEPTION? Nervousness Bradycardia Weight loss Sweating

Answer 25

Bradycardia

Question 26

What medication most likely has contributed to the patient's current findings? Reports moderate-severe muscle pain and darkened, reddish urine

Answer 26

Statins

Question 27

Which of the following is the mechanism of action of a statin?

Answer 27

Reduces liver production of cholesterol

Question 28

All of the following are potential side effects of furosemide (Lasix®) EXCEPT one. Which is the EXCEPTION? Hypokalemia Hearing loss Hypercalcemia Interstitial nephritis

Answer 28

Hypercalcemia

Question 29

Persistent dry cough is a side effect of which of the following drugs? Lisinopril Triamterene Furosemide Hydrochlorothiazide

Answer 29

Lisinopril

Question 30

MOA of bisphosphonates

Answer 30

Inhibits osteoclasts