Pharmacology - Adverse Drug Reactions

Question 1

Coronary vasospasm

Answer 1

Cocaine, sumatriptan, ergot alkaloids

Question 2

Cutaneous flushing

Answer 2

VANC - Vancomycin, Adenosine, Niacin, Ca2+ channel blockers

Question 3

Dilated cardiomyopathy

Answer 3

Doxorubicin, daunorubicin

Question 4

Torsades

Answer 4

Class III, Class IA, Antiarrhythmics, macrolides, antipsychotics, TCAs, fluoroquinolones

Question 5

Adrenocortical insufficiency

Answer 5

HPA axis suppression secondary to glucocorticoid withdrawal

Question 6

Hot flashes

Answer 6

Clomiphene (treats ovulation problems in women who want tobecome pregnant), tamoxifen

Question 7

Hyperglycemia

Answer 7

Nick Takes Sweet Betafish to Court and Hides them as a Prank

Niacin, Tacrolimus, (Hyperglycemia), Beta-blockers, Corticosteroids, HCTZ, Protease inhibitors

Question 8

Hypothyroidism

Answer 8

Lithium, amiodarone, sulfonamides

Question 9

Acute cholestatic hepatitis with jaundice

Answer 9

Erythromycin

Question 10

Diarrhea

Answer 10

Medicines acting erratically on colon

Metformin, acarbose, erythromycin, orlistat, colchicine

Question 11

Hepatitis

Answer 11

INH

Question 12

Focal to massive hepatic necrosis

Answer 12

Halothane, Amanita phalloides (death cap mushroom), VPA, Acetaminophen
HAVAc

Question 13

Pancreatitis

Answer 13

As Val Did Alcohol at Court, she Died going Glp

Azathioprine, VPA, Didanosine, Alcohol, Corticosteroids, Diuretics, Glp-1

Question 14

Pseudomembranous colitis

Answer 14

Clindamycin, ampicillin, cephalosporins

Question 15

Agranulocytosis

Answer 15

Granny causes problems in dapper colorful clothes, methinks

Carbemazepine, propylthiouracil, dapsone, colchicine, clozaril, mehtimazole

Question 16

Aplastic anemia

Answer 16

Proper Nuns Chlorinate the Car (a Mercedes Benz)

Propylthiouracil, NSAIDS, Chloramphenicol, Carbemazepine, Methimazole, Benzene

Question 17

Direct coombs positive hemolytic anemia

Answer 17

Methyldopa (this is the alpha 2 agonist)

Penicillin

Question 18

Gray baby syndrome

Answer 18

Chloramphenicol

Question 19

Hemolysis in G6PD

Answer 19

INH, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

Question 20

Megaloblastic anemia

Answer 20

Phenytoin, Methotrexate, Sulfa drugs

Having a BLAST with PMS

Question 21

Thrombocytopenia

Answer 21

Heparin, cimetidine

Question 22

Thrombotic complications

Answer 22

OCPs

Question 23

Fat redistribution

Answer 23

Protease inhibitors, Glucocorticoids

Question 24

Gingival hyperplasia

Answer 24

Phenytoin, verapamil, cyclosporine, nifedipine

Question 25

Hyperuricemia (gout)

Answer 25

Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine, Topirimate

Question 26

Myopathy

Answer 26

Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon-alpha, penicillamine, statins, glucocorticoids

Question 27

Osteoporosis

Answer 27

Corticosteroids, heparin

Question 28

Photosensitivity

Answer 28

Sulfonamides, Amiodarone, Tetracyclines, 5-FU | SAT For Photo

Question 29

Rash / SJS

Answer 29

Ethosuximide, Carbamazepine, Lamotrigine, Phenytoin, Phenobarbital, Allopurinol, Sulfa drugs, Penicillin Stephen Johnson has epileptic Allergy to Sulfa Drugs and Penicillin

Question 30

SLE-like syndrome

Answer 30

Sulfa drugs, Hydralazine, INH, Procainamide, Phenytoin, Etanercept Having Lupus is SHIPP-E

Question 31

Teeth discoloration

Answer 31

Tetracyclines

Question 32

Tendonitis, tendon rupture, cartilage damage

Answer 32

Fluoroquinolones

Question 33

Cinchonism (temporary deafness, ringing in ears, headache, dizziness, rash)

Answer 33

Quinidine, quinine

Question 34

Parkinson-like syndrome

Answer 34

Antipsychotics, reserpine, metoclopramide | Cogwheel rigidity of the ARM

Question 35

Seizures

Answer 35

INH, Buproprion, Imipenem/Cilastatin, tramadol, enflurane, metoclopramide With seizures, I BITE My tongue.

Question 36

Tardive dyskinesia

Answer 36

Antipsychotics, metoclopromide

Question 37

Diabetes insipidus

Answer 37

Lithium, demeclocycline

Question 38

Fanconi syndrome

Answer 38

Expired tetracycline

Question 39

Hemorrhagic cystitis

Answer 39

Cyclophosphamide, ifosfamide (prevent by coadministering with mesna)

Question 40

Interstitial nephritis

Answer 40

``` DRiPS N Diuretics Rifampin Penicillins/beta lactam Sulfonamides NSAIDs ``` Dying pens suffer rightfully, nuffsaid.

Question 41

SIADH

Answer 41

Carbamazepine, Cyclophosphamide, SSRIs | Can't concentrate Serum Sodium

Question 42

Dry cough

Answer 42

ACEI

Question 43

Pulmonary fibrosis

Answer 43

Bleomycin, Amiodarone, Busulfan, Methotrexate | But Sultan, Allmy Melons Bloomed (and gave me a coughing fit)

Question 44

Antimuscarinic

Answer 44

Atropine, TCAs, H1 blockers, antipsychotics

Question 45

Disulfiram like reaction

Answer 45

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

Question 46

Nephrotoxicity/ototoxicity

Answer 46

Aminoglycosides, vancomycin, loop diuretics, cisplatin

Question 47

Sulfa drugs

Answer 47

Probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamides, sulfasalazine, sulfonylureas So basically the thiazides plus furosemide plus acetazolamide plus anything with a sulfa And celecoxib and probenecid for... some reason...