Pharmacology - Adverse Drug Reactions Flashcards Preview

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Flashcards in Pharmacology - Adverse Drug Reactions Deck (47)
1

Coronary vasospasm

Cocaine, sumatriptan, ergot alkaloids

2

Cutaneous flushing

VANC - Vancomycin, Adenosine, Niacin, Ca2+ channel blockers

3

Dilated cardiomyopathy

Doxorubicin, daunorubicin

4

Torsades

Class III, Class IA, Antiarrhythmics, macrolides, antipsychotics, TCAs, fluoroquinolones

5

Adrenocortical insufficiency

HPA axis suppression secondary to glucocorticoid withdrawal

6

Hot flashes

Clomiphene (treats ovulation problems in women who want tobecome pregnant), tamoxifen

7

Hyperglycemia

Nick Takes Sweet Betafish to Court and Hides them as a Prank
Niacin, Tacrolimus, (Hyperglycemia), Beta-blockers, Corticosteroids, HCTZ, Protease inhibitors

8

Hypothyroidism

Lithium, amiodarone, sulfonamides

9

Acute cholestatic hepatitis with jaundice

Erythromycin

10

Diarrhea

Medicines acting erratically on colon
Metformin, acarbose, erythromycin, orlistat, colchicine

11

Hepatitis

INH

12

Focal to massive hepatic necrosis

Halothane, Amanita phalloides (death cap mushroom), VPA, Acetaminophen
HAVAc

13

Pancreatitis

As Val Did Alcohol at Court, she Died going Glp

Azathioprine, VPA, Didanosine, Alcohol, Corticosteroids, Diuretics, Glp-1

14

Pseudomembranous colitis

Clindamycin, ampicillin, cephalosporins

15

Agranulocytosis

Granny causes problems in dapper colorful clothes, methinks
Carbemazepine, propylthiouracil, dapsone, colchicine, clozaril, mehtimazole

16

Aplastic anemia

Proper Nuns Chlorinate the Car (a Mercedes Benz)
Propylthiouracil, NSAIDS, Chloramphenicol, Carbemazepine, Methimazole, Benzene

17

Direct coombs positive hemolytic anemia

Methyldopa (this is the alpha 2 agonist)
Penicillin

18

Gray baby syndrome

Chloramphenicol

19

Hemolysis in G6PD

INH, Sulfonamides, Dapsone, Primaquine, Aspirin, Ibuprofen, Nitrofurantoin

20

Megaloblastic anemia

Phenytoin, Methotrexate, Sulfa drugs
Having a BLAST with PMS

21

Thrombocytopenia

Heparin, cimetidine

22

Thrombotic complications

OCPs

23

Fat redistribution

Protease inhibitors, Glucocorticoids

24

Gingival hyperplasia

Phenytoin, verapamil, cyclosporine, nifedipine

25

Hyperuricemia (gout)

Pyrazinamide, Thiazides, Furosemide, Niacin, Cyclosporine, Topirimate

26

Myopathy

Fibrates, Niacin, Colchicine, Hydroxychloroquine, Interferon-alpha, penicillamine, statins, glucocorticoids

27

Osteoporosis

Corticosteroids, heparin

28

Photosensitivity

Sulfonamides, Amiodarone, Tetracyclines, 5-FU
SAT For Photo

29

Rash / SJS

Ethosuximide, Carbamazepine, Lamotrigine, Phenytoin, Phenobarbital, Allopurinol, Sulfa drugs, Penicillin

Stephen Johnson has epileptic Allergy to Sulfa Drugs and Penicillin

30

SLE-like syndrome

Sulfa drugs, Hydralazine, INH, Procainamide, Phenytoin, Etanercept

Having Lupus is SHIPP-E

31

Teeth discoloration

Tetracyclines

32

Tendonitis, tendon rupture, cartilage damage

Fluoroquinolones

33

Cinchonism (temporary deafness, ringing in ears, headache, dizziness, rash)

Quinidine, quinine

34

Parkinson-like syndrome

Antipsychotics, reserpine, metoclopramide
Cogwheel rigidity of the ARM

35

Seizures

INH, Buproprion, Imipenem/Cilastatin, tramadol, enflurane, metoclopramide

With seizures, I BITE My tongue.

36

Tardive dyskinesia

Antipsychotics, metoclopromide

37

Diabetes insipidus

Lithium, demeclocycline

38

Fanconi syndrome

Expired tetracycline

39

Hemorrhagic cystitis

Cyclophosphamide, ifosfamide (prevent by coadministering with mesna)

40

Interstitial nephritis

DRiPS N
Diuretics
Rifampin
Penicillins/beta lactam
Sulfonamides
NSAIDs

Dying pens suffer rightfully, nuffsaid.

41

SIADH

Carbamazepine, Cyclophosphamide, SSRIs
Can't concentrate Serum Sodium

42

Dry cough

ACEI

43

Pulmonary fibrosis

Bleomycin, Amiodarone, Busulfan, Methotrexate
But Sultan, Allmy Melons Bloomed (and gave me a coughing fit)

44

Antimuscarinic

Atropine, TCAs, H1 blockers, antipsychotics

45

Disulfiram like reaction

Metronidazole, certain cephalosporins, griseofulvin, procarbazine, 1st generation sulfonylureas

46

Nephrotoxicity/ototoxicity

Aminoglycosides, vancomycin, loop diuretics, cisplatin

47

Sulfa drugs

Probenecid, furosemide, acetazolamide, celecoxib, thiazides, sulfonamides, sulfasalazine, sulfonylureas

So basically the thiazides plus furosemide plus acetazolamide plus anything with a sulfa
And celecoxib and probenecid for... some reason...