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Flashcards in Pharmacology - Antidotes Deck (24)
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Acetaminophen

N-acetylcysteine (replenishes glutathione)

1

AChE inhibitors

Atropine followed by pralidoxime

2

Organophosphates

Atropine followed by pralidoxime

3

Amphetamines

NH4Cl (acidify the urine)

4

Antimuscarinic, anticholinergic agents

Physostigmine salicylate, controls hyperthermia

5

Benzodiazepines

Flumenazil

6

Beta blockers

Glucagon

7

Carbon monoxide

100 percent oxygen or hyperbaric o2

8

Copper

Penicillamine

9

Arsenic

Penicillamine

10

Gold

Penicillamine

11

Cyanide

Nitrite and thiosulfate or hydroxocobalamin

12

Digitalis

Anti digitalis fab fragments

13

Heparin

Protamine sulfate

14

Iron

Deferoxamine, deferasirox

15

Lead

EDTA
Dimercaprol
Succimer
Penicillamine

16

Mercury, arsenic, gold

Dimercaprol (BAL), succimer

17

Methanol or ethylene glycol

Fomepizol > ethanol

Dialysis

18

Methemoglobin

Methylene blue

Vitamin c

19

Opioids

Naloxone

20

Salicylates

Sodium bicarb to alkalinize urine
Then dialysis

21

Tricyclic antidepressants

Sodium bicarb for plasma alkalinization

22

Tissue plasminogen activator
Streptokinase
Urokinase

Aminocaproic acid

23

Warfarin

Vitamin k
Plasma, if active bleeding