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Flashcards in Repro - Pictures Deck (46)
1

 

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Seminoma - note the fried eggs, maybe...

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Schiller duval body - associated with yolk sac tumor

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Schiller duval body - associated with yolk sac tumor

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Reinke crystal associated with Leydig cell tumor

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Schiller duval body 

Schiller-Duval body is a distinctive perivascular structure seen in the endodermal sinus pattern of yolk sac tumor. It consists of a central vessel

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Bowenoid papulosis - reddish papules associated with squamous cell carcinoma

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Erythroplasia of Queyrat - associated with squamous cell carcinoma

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Erythroplakia

Erythroplakia (also termed erythroplasia)[1]:734 is a clinical term to describe any erythematous (red) area on a mucous membrane,[2] that cannot be attributed to any other pathology.[3]:805

The term erythroplasia was coined by Louis Queyrat to describe a precancerous red lesion of the penis.[4] This gave rise to the termerythoplasia of Queyrat.

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Bowen disease

Squamous cell carcinoma in situ

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Choriocarcinoma

Choriocarcinoma is an uncommon testicular germ cell tumor that is usually seen as a component of mixed germ cell tumor. 

 

Syncytiotrophoblastic and cytotrophoblastic elements

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Embryonal carcinoma - malignant, hemorrhagic mass with necrosis - often glandular or papillary morphology

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Invasive lobular carcinoma - orderly row of cells in indian file position - often bilateral with multiple lesions in the same location

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Invasive lobular breast carcinoma - Indian file

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Peau d'orange - breast skin resembles orange peel - dermal lymphatic invasion by breast carcinoma

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Another example of a poorly differentiated invasive ductal carcinoma. The arrow points to a multinucleated tumor giant cell. 

16

Which breast cancer is most common?

Invasive dustal carcinoma - 76% of all breast cancers

It is also the worst and most invasive

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What is the cell indicated by the arrow? Paget cell-- large cells in epidermis with clear halo

 

Suggests underlying ductal carcinoma in situ

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Paget cells  - suggests underlying DCIS

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Benign Phyllodes tumor of the breast - large bulky mass of connective tissue and cysts with leaf-like projections. Most common in the 6th decade. Some may be malignant.

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Benign Phyllodes tumor of the breast - large bulky mass of connective tissue and cysts with leaf-like projections. Most common in the 6th decade. Some may be malignant.

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Sarcoma botryoides (rhabdomyosarcoma variant)

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Sarcoma botryoides (rhabdomyosarcoma variant) - occurs in girls < 4 vagina

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Vagina clear cell adenocarcinoma

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Krukenberg Tumor

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Breast Comedocarcinoma, Medium Power Microscopic. The cells in the center of the ducts with comedocarcinoma are often necrotic and calcify

 

Ductal, central necrosis

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Comedocarcinoma

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Brenner tumor of ovary

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struma ovarii

Mature cystic teratoma that can also contain functional thyroid tissue and present as hyperthryoidism

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Meigs syndrome

Ovarian fibroma, ascites, hydrothorax (trio)

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Mucinous cystadenoma

31

Which cyst is associated with choriocarcinoma and moles?

Theca-lutein cyst

32

What gene product does HPV 16 and HPV 18 produce?

E6 - inhibits p53

E7 - inhibits RB suppressor gene

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Human papillomavirus-induced condylomatous infections. Biopsy of the condyloma shows koilocytes with perinuclear halos but lacking nuclear atypia.

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Endometritis

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Snowstorm on ultrasound - associated with complete mole

36

How do you treat acute mastitis?

Dicloxacillin, usually staph aureus

37

What drugs cause gynecomastia?

Some Dope drugs easily create awkward hairy DD knockers

Spironolactone, Dope, Digitalis, Estrogen, Cimetidine, Alcohol, Heroin, Dopamine D2, Ketoconazole

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What are two tumor markers for prostatic adenocarcinoma?

PAP - prostatic acid phosphatase

PSA - prostate specific antigen

39

What is the most common testicular tumor?

Seminoma

40

Increased placental ALP in a painless testicular enlargement should make one think... 

Seminoma, possibly mixed embryonal carcinoma

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Increased hCG in a testicular tumor should make you think of

Choriocarcinoma, Teratoma, Embryonal carcinoma

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Hematogenous metastasis to lungs and brain in a testicular tumor should make you think of?

Choriocarcinoma

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Gynecomastia and hyperthyroidism in a testicular tumor should make you think of?

Choriocarcinoma

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Malignant hemorrhagic painful testicular tumor should make you think of?

Embryonal carcinoma

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Most common testicular cancer in older men?

Testicular lymphoma

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