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Porcine Flash - Porcine Stress Syndrome Flashcards

(8 cards)

1
Q

what is the underlying cause of malignant hyperthermia in pigs?

A

mutation at the ryanodine receptor on calcium channels of the sarcoplasmic reticulum - autosomal recessive in pigs

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2
Q

what are the clinical signs of porcine stress syndrome?

A

sudden death in several pigs in periods of stress, muscle stiffness/rapidly increasing temperatures, & increased CO2 in a pig during inhalant anesthesia, metabolic & respiratory acidosis with red mottled skin

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3
Q

how do you treat malignant hyperthermia in an anesthetized pig?

A

stop inhalant/procedure, IV dantrolene (muscle relaxant), body cooling, & IV fluids

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4
Q

how is anesthesia linked to porcine stress syndrome?

A

inhalant anesthetics are known triggers

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5
Q

what is the test of choice for diagnosing porcine stress syndrome? what are some other choices?

A

genetic testing!!!! also, history/clinical signs, history of anesthesia, & elevated creatine kinase levels

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6
Q

what is the common terminology used to describe muscles on pigs with porcine stress syndrome?

A

pale, soft, & exudative

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7
Q

what pigs are more often affected by PSS?

A

heavy muscled breeds

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8
Q

what is the pathogenesis behind porcine stress syndrome?

A

hypermetabolic syndrome of skeletal muscles - uncontrolled calcium release from sarcoplasmic reticulum in myocytes which leads to muscle contraction - muscle metabolism goes crazy producing heat, lactate, CO2, & acidosis

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