Primary Sclerosing Cholangitis Flashcards Preview

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Flashcards in Primary Sclerosing Cholangitis Deck (6)
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1

whats it characterised by?

progressive obliterating fibrosis of intra- and extra hepatic ducts

eventually leading to cirrhosis

2

associations

ulcerative colitis

3

diagnosis

usually by MRCP or LFT

most commonly after routine blood testing in IBD patient

increased alkaline phosphatase
then increased bilirubin

4

symptomatic presentation

itching, pain, rigours, or jaundice

5

Mx

Mx of CLD
transplantation
ursodeoxycholic acid

ERCP of extra hepatic strictures

6

how is it related to AIDS?

Sclerosing cholangitis secondary to cryptosporidium infection seen in pts with AIDS