Progestin Only Contraceptives Flashcards
(9 cards)
1
Q
Therapeutic Class
A
contraceptive
2
Q
examples
A
norethidrone (Micronor)
3
Q
mechanism of action
A
Inhibitory cervical mucus changes including increased viscosity & cell content, with inhibition of sperm transport or migration. Suppresses FSH & LH anovulation Endometrial changes (progestational) which is unfavorable to implantation
4
Q
Actions and Uses
A
Contraception
Used in women who are unable to take estrogen
Used most frequently during lactation (estrogen decreases lactation supply)
5
Q
Adverse Effects
A
Ectopic pregnancy, ovarian cysts, breast carcinoma, headache, irregular vaginal bleeding
6
Q
Black Box Warning
A
Cigarette smoking increases risk of CV adverse effects, risk increases > 35y/o & heavy smoking > 15 cigarettes/day
7
Q
Contraindications
A
Breast cancer, undiagnosed irregular bleeding, liver tumors
8
Q
Interactions
A
May decrease Progestins: carbamazepine, phenobarbital, phenytoin, rifampin, benzodiazepines, barbiturates
Reduce effect: St. John’s wort
9
Q
Preg Cat
A
X
