Vaginal Device

Question 1

Therapeutic Class

Answer 1

Hormonal vaginal contraceptive

Question 2

Example

Answer 2

ethinyl estradiol + etonogestrel (NuvaRing)

Question 3

Mechanism of Action

Answer 3

combination of both drugs

Question 4

Actions and Uses

Answer 4

Insert & leave in place x 3 weeks, remove for 1 ring free week

Question 5

Adverse Effects

Answer 5

DVT, PE, CVA, MI

Expulsion, discomfort, foreign body sensation

Question 6

Black Box Warning

Answer 6

Cigarette smoking increases risk of CV adverse effects, risk increases > 35y/o & heavy smoking > 15 cigarettes/day

Question 7

Contraindications

Answer 7

Thromboembolic disorders, stroke, coronary artery disease, hepatic tumors; carcinoma of breast, uterus or ER or PR dependent tumors, pregnancy

Question 8

Interactions

Answer 8

Decreased efficacy: rifampin, antibiotics, barbiturates, anticonvulsants, protease inhibitors, antifungals
Breakthrough bleeding: St. John’s wort

Question 9

Preg Cat

Answer 9

X