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Flashcards in Rapid-Fire Facts Deck (244)
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1

MCC neural tube defects

folate deficiency

2

MC preventable cause of congenital malformations in US

fetal alcohol syndrome

3

hyperflexible joints, arachnodactyly, aortic dissection, lens dislocation

Marfan syndrome

4

hereditary nephritis, cataracts, sensorineural hearing loss

Alport syndrome

5

"worst headache of my life"

SAH

6

lucid interval following head trauma

epidural hematoma

7

bloody CSF following head trauma

epidural hematoma

8

bloody CSF on LP

SAH

9

MCC subdural hematoma

rupture of bridging veins

10

MCC epidural hematoma

rupture of MMA

11

MCC dementia

Alzheimer's disease

12

second MCC dementia

vascular dementia

13

extracellular amyloid deposits in gray matter

amyloid plaques

14

intracellular deposits of hyperphosphorylated tau protein

neurofibrillary tangles

15

intracellular spherical aggregates of tau protein seen on silver stain

Pick bodies

16

treatment for absence seizures

ethosuximide

17

conjugate lateral gaze palsy, with nystagmus and diplopia during lateral gaze

internuclear ophthalmoplegia

18

degeneration of dorsal columns

tabes dorsalis

19

demyelinating disease in a young woman

multiple sclerosis

20

mixed upper and lower motor neuron disease

amyotrophic lateral sclerosis

21

depigmentation of substantia nigra

Parkinson's disease

22

chorea, dementa and atrophy of the caudate and putamen

Huntington disease

23

eosinophilic inclusions in the cytoplasm of neurons

Lewy bodies

24

toe extension upon stimulating the sole of the foot with a blunt instrument

(+) Babinski reflex

25

amyloid deposits in gray matter of brain

senile plaques (Alzheimer's disease)

26

drooling farmer

organophosphate poisoning

27

medical treatment for pheochromocytoma

alpha antagonists

28

selective alpha1-antagonist used to treat BPH

tamsulosin (or -zosins)

29

four pharmacokinetic equations

Vd = D/C (Vd: volume of distribution; D: IV drug concentration; C: plasma concentration of drug)
CL = rate of elimination/plasma concentration = (0.7 x Vd)/t1/2 = K x Vd (CL: clearance; K: elimination constant)
LD = Css x Vd (LD: loading dose; Css: concentration at steady state)
MD = Css x CL (MD: maintenance dose)

30

continuous, machine-like heart murmur

PDA