RATE-LIMITING STEPS Flashcards Preview

#‼️BIOCHEMISTRY - PLE TOPNOTCH 2020 > RATE-LIMITING STEPS > Flashcards

Flashcards in RATE-LIMITING STEPS Deck (11)
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1

rate liming step of Lipogenesis

Acetyl CoA + HCO 3 – + ATP → Malonyl CoA 

Enzyme: Acetyl CoA carboxylase​

2

Rate limiting enzyme for PURINE SYNTHESIS

• PRPP glutamyl amidotransferase

3

Which step is rate-limiting in TCA cycle?

Isocitrate → α-ketoglutarate 

Enzyme: Isocitrate dehydrogenase

4

rate limiting step of KETOGENESIS

Acetoacetyl CoA + Acetyl CoA → HMG CoA 

Enzyme: HMG CoA Synthase​

5

Rate limiting step of BETA-OXIDATION or LIPOLYSIS. 

Translocation of fatty acyl CoA from the cytosol to the mitochondria 

Enyzme: Carnitine-palmitoyl transferase​

6

Which step is rate-limiting in PPP?

Glucose-6-phosphate → 6-phosphogluconate 

Enzyme: Glucose-6-phosphate dehydrogenase (G6PD)

7

Rate limiting step for Cholesterol Synthesis

Hydroxymethylglutaryl-CoA (HMG CoA) → Mevalonate 

Enzyme: HMG-CoA Reductase Requirement: 2 NADPH​

8

Which step is rate-limiting step of glycolysis?

Fructose-6-phosphate → Fructose-1,6-bisphosphate 

Enzyme: Phosphofructokinase-1

9

What is the rate-limiting step of Glycogenesis?

Elongation of glycogen chains i.e., creation of α-(1,4) glycosidic bonds Enzyme: Glycogen synthase

10

What is the rate limiting step in Gluconeogenesis?

Fructose 1,6-bisphosphate → Fructose 6-phosphate 

Enzyme: Fructose 1,6-bisphosphatase

11

Rate-limiting step of UREA CYCLE 

NH 3 + CO 2 → Carbamoyl phosphate 

Enzyme: Carbamoyl phosphate synthetase I 

Allosteric Activator: N-acetylglutamate