rate liming step of Lipogenesis
Acetyl CoA + HCO 3 – + ATP → Malonyl CoA
Enzyme: Acetyl CoA carboxylase
Rate limiting enzyme for PURINE SYNTHESIS
• PRPP glutamyl amidotransferase
Which step is rate-limiting in TCA cycle?
Isocitrate → α-ketoglutarate
Enzyme: Isocitrate dehydrogenase
rate limiting step of KETOGENESIS
Acetoacetyl CoA + Acetyl CoA → HMG CoA
Enzyme: HMG CoA Synthase
Rate limiting step of BETA-OXIDATION or LIPOLYSIS.
Translocation of fatty acyl CoA from the cytosol to the mitochondria
Enyzme: Carnitine-palmitoyl transferase
Which step is rate-limiting in PPP?
Glucose-6-phosphate → 6-phosphogluconate
Enzyme: Glucose-6-phosphate dehydrogenase (G6PD)
Rate limiting step for Cholesterol Synthesis
Hydroxymethylglutaryl-CoA (HMG CoA) → Mevalonate
Enzyme: HMG-CoA Reductase Requirement: 2 NADPH
Which step is rate-limiting step of glycolysis?
Fructose-6-phosphate → Fructose-1,6-bisphosphate
What is the rate-limiting step of Glycogenesis?
Elongation of glycogen chains i.e., creation of α-(1,4) glycosidic bonds Enzyme: Glycogen synthase
What is the rate limiting step in Gluconeogenesis?
Fructose 1,6-bisphosphate → Fructose 6-phosphate
Enzyme: Fructose 1,6-bisphosphatase
Rate-limiting step of UREA CYCLE
NH 3 + CO 2 → Carbamoyl phosphate
Enzyme: Carbamoyl phosphate synthetase I
Allosteric Activator: N-acetylglutamate