Session 7 - E.Coli Flashcards Preview

Semester 3 - Urinary > Session 7 - E.Coli > Flashcards

Flashcards in Session 7 - E.Coli Deck (16):
1

Where is e.coli usually found?

Routinely found in the gastrointestinal tract of humans and animals, as well as being found in soil and water.

2

What is the gram stain of e.coli?

-'ve

3

What shape is e.coli?

Rod shaped

4

What is the capsule of e.coli made of?

Lipopolysaccharide

5

How does e.coli respire?

Falculatative anaerobe

6

Give one special feature of e.coli

Posseses pili which are important for adherence to host

7

Give three diseases caused by e.colie

Travellers diarrhoea
UTI
Neonatal meningitis

8

Give two ways of getting an e.coli infection

Transmission from own colonies
Picking up other strains through faecal-oral transmission

9

How does e.coli cause travellers diarrhoea?

Enterotoxigenic e.coli
• Occurs due to contamination of human waste with faecal matter, or through person to person contact. ETEC colonise small intestine and secrete enterotoxins which cause hypersecretion of chloride ions and water by intestinal mucosal cells. Causes watery diarrhoea.

10

How does e.coli cause UTI?

• Patients own E. Coli travel to bladder via perineum and then urethra. Can cause cystitis and pyelonephritis in women

11

How does e.coli cause neonatal meningitis

E.coli acquired from mother during birth

12

How do you test for e.coli in travellers diarrhoea?

PCR of e.coli
Stool sample

13

How do you test for extraintestinal disease caused by e.coli (UTI/meningitis)

Isolation of e.coli from normally sterile locations

14

How do you treat travellers diarrhoea?

Oral rehydration

15

What antibiotic is used to treat UTI?

Ciprofloxacin

16

What antibiotic is used to treat neonatal meningitis

Cefotaximine