The Endocrine System 2 Flashcards Preview

Hormones And Behaviour > The Endocrine System 2 > Flashcards

Flashcards in The Endocrine System 2 Deck (12)
Loading flashcards...
1

How were hormones historically measured?

Bioassays e.g. frog based pregnancy tests

2

What is now used to measure hormones?

Immunoassay and radioimmunoassay

3

How does radioimmunoassay work?

Purified hormone radioactively labelled and mixed with unlabelled hormone to compete for binding to antibody
High % of bound labelled hormone indicated low amount of unlabelled hormone

4

What else has been developed due to the concerns with using radioactive labels?

Labels that produce a colour change e.g. enzymeimmunoassays (EIA) and enzyme-linked immunosorbent assays (ELISA)

5

What is the basis of current home pregnancy tests?

An EIA variant

6

What is the disadvantage of antibody-based methods?

They may cross react with related molecules giving misleading results

7

What does it mean by endocrine glands are ductless?

The products are secreted directly into blood

8

What are most hormones? (Proteins, steroids or amines?)

Proteins

9

How are proteins, steroids and amines produced?

Protein hormones produced by gene transcription and translation

Steroids and amines synthesised by enzymes

10

What are neurohormones that control hormone production by the pituitary gland called?

Give and example

Releasing hormones or factors

Gonadotropin releasing hormone (GnRH)

11

Where are steroid hormones produced in male testes?

Produced by Leydig cells, lying between the seminiferous tubules (where sperm production takes place)

12

What promotes the conversion of androgens to oestrogens in females?

FSH receptors in the granulosa cell