tobacco Flashcards

(63 cards)

1
Q

what is the most dangerous substance in the world?

A

tobacco (kills more people than cocaine, homicide, suicide, etc combined)

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2
Q

how much does tobacco kills how many per year in NA?

A

480,000

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3
Q

what is the life expectancy of a smoker

A

73 years

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4
Q

what happens if you quit smoking before age 30??

A

adds 10 years to lifespan

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5
Q

what does smoking count for in health care costs

A

6-15%

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6
Q

who discovered tobacco

A

Columbus 1492

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7
Q

what did tobacco used to revive?

A

drowning victims

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8
Q

cigarette were originally rolled by ???

A

hand

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9
Q

what reduced production cost

A

bonsack machine

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10
Q

what reduced harshness of smoke

A

flue-curing

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11
Q

how did cigarettes become dangerous?

A

could afford to smoke a lot and smoke brought deep into lungs (flue curing reduced)

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12
Q

average smoker smoked ____ cigarettes each year from 1800’s?

A

10,000 (inhales) vs 80 (didn’t inhale)

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13
Q

what is the addictive substance

A

nicotine (2 mg per cig)

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14
Q

how does nicotine work in body?

A

acts on acetylcholine receptors

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15
Q

what do receptor molecules do

A

transmit info

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16
Q

how do receptor molecules transmit info

A

messenger molecule sticks to a complimentary pocket on receptor

messenger binding causes receptor to change shape

new receptor shape triggers other events inside the cell

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17
Q

nicotine is an agonist at

A

low doses

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18
Q

how does agonists work

A

send messages without normal messenger

sticks and binds to change shape

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19
Q

nicotine is an antagonist at ????

A

high doses

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20
Q

what do antagonists do

A

block chemical messages

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21
Q

what do smokers learn to do

A

regulate the dose

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22
Q

nicotine stimulates the ??

A

dopamine release

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23
Q

what is lethal dose of nicotine

A

60 mg

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24
Q

can nicotine kill large animals

A

yes

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25
what is the toxic substances in tobacco smoke
carbon monoxide (blocks oxygen transport and damages heart tissue)
26
what does nicotine stimulate
heart muscle (increases heart attack)
27
what causes cancer in tobacco smoke
carcinogens - polonium
28
what does carcinogenicity react
chemicaaly with DNA
29
who linked cancer to smoking 1919
alton ochsner
30
lung cancer in 1919 vs 2004?
400 cases vs 190,000 cases
31
who did tobacco advertising originally target?
men (started for women in 1950s)
32
who were cigarettes provided free to
soldiers
33
why did women start smoking
to stay slim
34
when smokers quit smoking what do they do?
eat more
35
what does smoking create
wrinkles and ages skin
36
how many people die from second hand smoke
41,000 a year
37
what are cigarettes
highly engineered drug delivery device
38
how is paper designed
control burning by chemical additives and burn rings regulate combustion (filter is decoration)
39
what are light cigarettes designed for
lab testing
40
are light and regular cigarettes the same??
yes
41
Florida sues ????
big tobacco in 1998
42
what does e-cig do
heater generates an aerosol
43
what is efluid
flavoured vapor source
44
what creates the appearance of smoke
solvent droplets
45
cartridge = ____ cigs?
10
46
what type of flavour does nicotine have
bitter taste
47
what are nicotine salts for
replacement
48
what are salts designed for
replicate fast action of nicotine from cig (may provide harm reduction) FAST
49
nicotine pods last ???
many hours
50
is vaping safe?
no
51
is vaping safer than cigs? (95% harm reduction)
yes bc e-cig only has nicotine, carbonyl compounds and glycols where cigs have more
52
what makes testing difficult
large number of combos
53
active ingredients in canabis?
Tetrahydrocannabinol Cannabidiol
54
what is side effect of THC
increased appetite (for anorexia) and impairs memory slows reaction times
55
why does THC have a long residence time
dissolved in body fat
56
edible versions now legal??
yes but more problematic for side effects
57
edibles give a ??
delayed effect
58
THC solutions _____ when concentrated
thicken because of vitamin E
59
what is a grey market product
nicotine and cannabis
60
heavy use may lead to ????
schizophrenia bc THC causes inc in dopamine
61
marijuana has ?/
cannabidiol
62
what is cannabinoid hyperemesis syndrome?
severe abdominal pain, nausea, vomitinhg
63
what is delta -8
synthetic cannabinoid