Fasciola hepatica
Host: Herbivorous animals (cows)
Location: Common bile duct
1st IH: Lymnaea truncatula
2nd IH: Metacercariae on vegetation
There does appear to be resistance of F. hepatica to triclabendazole
Clorsulon only thing available in USA
Albendazole from cattle at a dosage rate of 10 mg/kg of body weight and from sheep at 7.5 mg/kg.
USA
Fasciolidae
Fascioloides magna
Host: WTD
Location: Liver in cysts that connect with bile duct
1st IH: Lymnaeid snail (e.g. Galba or Lymnaea spp.)
2nd IH: Metacercariae on vegetation
USA and Europe
Fasciolidae
Fasciola gigantica
Host: Domestic ruminants (cattle, buffalo, goats, sheep) & humans
Location Bile ducts
1st IH: lymnaeid snails
2nd IH: Metacercariae on vegetation
Only in Africa
Fasciolidae
Fasciolopsis buski
Host: Humans and pigs
Location: Small intestine
1st IH: Segmentina, Hippeutis, Gyraulus species
2nd IH: Metacercariae on vegetation
Asia
Fasciolidae
Paramphistomum cervi
Rumen fluke
Host: Ruminants
Location: Rumen
1st IH: Physa, Bulinus, Galba, and Pseudosuccinea
2nd IH: Metacercariae on vegetation
Clorsulon at 2 mg/kg in combination with ivermectin at 0.2 mg/kg was ineffective in treating immature rumen flukes
Paramphistomidae
Cotylophoron sp.
Rumen fluke
Host: Ruminants
Location: Rumen
1st IH: Bulinus or Indoplanorbis species
2nd IH: Metacercariae on vegetation
Paramphistomidae
Calicophoron calicophorum
Rumen fluke
Host: Ruminants
Location: Rumen
1st IH: Bulinus or Indoplanorbis species
2nd IH: Metacercariae on vegetation
Hexachlorophene in a single dose of 20 mg/kg and oxyclozanide in two doses of 19 mg/kg 3 days apart were highly efficient against juvenile and adult paramphistome flukes, in cattle
Paramphistomidae
Gastrodiscoides hominis
Host: Humans, pigs, and monkeys
Location:Cecum and colon
1st IH: Helicorbis spp.
2nd IH: Metacercariae on vegetation
Paramphistomidae
Nanophyetus salmincola
Host: Dogs & cats
Location: Intestines
1st IH: Oxytrema silicula,
2nd IH: salmonid fishes
Praziquantel, 7 to 38 mg administered subcutaneously or intramuscularly
PNW USA
Troglotrematidae; Transmits Salmon Poisoning Disease
Paragonimus kellicotti
Host: Dogs & cats
Location: Lungs, in pairs
1st IH: Pomatiopsis lapidaria
2nd IH: freshwater crabs and crayfish
Praziquantel, 23 mg/kg three times a day for 3 days or Fenbendazole, 50 mg/kg for 10 to 14 days
Eastern USA
Troglotrematidae
Cryptocotyle lingua
Host: gulls and terns, produces severe enteritis in dogs, foxes, and minks
Location: Intestine
1st IH: Littorina littorea
2nd IH: Fish (Cause “black spot disease”), this is in cunner
Heterophyidae
Metagonimus yokogawai
Host: Humans, dogs, cats, pigs, and other fish-eating mammals.
Location: Small intestine
1st IH: Semisulcospira spp., Thiara spp.
2nd IH: sweetfish Plecoglossus altivelis, carp, trout
Heterophyidae
Opisthorchis felineus
former name: Opisthorchis tenuicollis
Siberian liver fluke
Host: Fish-eating mammals, including humans, cats, dogs, foxes, pigs, and other carnivores.
Location: Bile ducts
1st IH: Bithynia tentaculata
2nd IH: Freshwater fish
Praziquantel in dogs and cats at 30 mg/kg orally once daily
Asia and Europe
Opisthorchiidae
Metorchis albidus
Host: Fox and pigs
Location: Bile ducts
1st IH: Bithynia tentaculata
2nd IH: Freshwater fish
USA
Opisthorchiidae
Parametorchis complexus
Host: Fox and pigs
Location: Bile ducts
1st IH: Bithynia tentaculata
2nd IH: Freshwater fish
Opisthorchiidae
Clonorchis sinensis
Host: Dogs and cats
Location: Bile ducts
1st IH: Bithynia tentaculata and Parafossarulus, Alocinma spp.
2nd IH: Freshwater fish
Asia
Opisthorchiidae
Dicrocoelium dendriticum
Host: sheep, cattle, pigs, deer, llamas, alpacas, woodchucks, and cottontail rabbits
Location: bile duct–> can cause fibrosis
1st IH: Cionella lubrica
2nd IH: Formica fusca (ant)
Albendazole administered orally to sheep at 15 to 20 mg/kg
Dicrocoeliidae
Platynosomum fastosum
Host: Cats
Location: Bile duct and gall bladder
1st IH: terrestrial snails
2nd IH: Pill bugs
Paratenic: lizards, toads, geckos, and skinks
associated with the development of cholangiocarcinomas in cats
Praziquantel 20 mg/kg markedly reduced the number of Platynosomum eggs passed in the feces of cats
Caribbean and Souther USA
Dicrocoeliidae
Eurytrema procyonis
Host: Raccoon, occasionally cats
Location: Pancreatic duct
1st IH: terrestrial snails
2nd IH: orthopteran insects (grasshoppers, crickets)
Paratenic: lizards, toads, geckos, and skinks
Dicrocoeliidae
Alaria canis
Host: Dogs and foxes
Location: Small intestine
1st IH: Helisoma
2nd IH: tadpole
praziquantel and probably epsiprantel
Diplostomidae
Alaria marcianae
Host: Cats
Location: Intestine
1st IH: Helisoma
2nd IH: tadpole
can migrate to the mammary gland in a lactating queen
praziquantel and probably epsiprantel
Diplostomatidae
Fibricola texensis
Host: Fish-eating mammals and birds (e.g., raccoons, mink, herons).
Location: Small intestine
1st IH: Helisoma
2nd IH: Amphibians or fish
Diplostomidae
Schistosoma haematobium
Host: Humans
Location: Veins of urinary baldder
1st IH: Bulinus spp.
Eggs have a terminal spine and are passed in urine
Africa and the Middle East.
Schistosomatidae
Schistosoma mansoni
Host: Human
Location: Mesenteric veins
Ist IH: Biomphalaria spp
Eggs have a lateral spine and are passed in feces
Africa, the Middle East, South America (notably Brazil), and the Caribbean
Schistosomatidae