DNA polymerase
enzymes that replicate and repair DNA
-DNA polymerase 3 is used on leading strand
-DNA polymerase 1 is used on lagging strand
Primase
enzyme that lays out RNA primer
-a short chain of RNA nucleotides
the new strand of DNA will use the RNA primer as a layout and lay DNA nucleotides (RNA nucletides are removed and replaced)
Leading vs lagging strand
Leading:
-uses 3 - 5 prime as template
-continuously synthesizes
-only needs 1 primer
-DNA polymerase 3
Lagging:
-uses 5 - 3 prime aas template
-synthesizes in fragments
-fragments = Okazaki fragments
-DNA ligase forms covalent bonds between the fragments to stablize them
-DNA polymerase 1