Urinary Tract Complications in Pregnancy Flashcards

(25 cards)

1
Q

What is asymptomatic bacteriuria?

A

Presence of multiplying bacteria in the urinary tract (excluding distal urethra) without symptoms.

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2
Q

What is the incidence of asymptomatic bacteriuria in pregnancy?

A

2–7%

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3
Q

What are the common risk groups for asymptomatic bacteriuria?

A

Women with sickle cell trait and diabetes.

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4
Q

What percentage of untreated asymptomatic bacteriuria progresses to pyelonephritis?

A

25–30%

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5
Q

How is asymptomatic bacteriuria diagnosed?

A

Colony count >10⁵ organisms/mL in 2 consecutive clean-catch samples.

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6
Q

What is the most common group of organisms in asymptomatic bacteriuria?

A

Gram-negative organisms.

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7
Q

What is acute pyelonephritis?

A

Infection of the renal pelvis and kidney, occurring in 1–2% of pregnancies.

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8
Q

What are the maternal symptoms of acute pyelonephritis?

A

Fever, chills, flank pain, nausea, vomiting, dysuria, frequency, leukocytosis, thrombocytopenia.

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9
Q

What are the foetal complications of acute pyelonephritis?

A

Prematurity, small-for-gestational age (SGA) babies.

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10
Q

What findings are seen in urine analysis in acute pyelonephritis?

A

Bacteriuria, pyuria, WBC casts, haematuria.

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11
Q

What is the treatment for acute pyelonephritis?

A

Hospital admission, IV antibiotics (e.g. nitrofurantoin, cephalosporins), fluids, antipyretics.

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12
Q

What is acute renal failure (ARF)?

A

Temporary loss of kidney function with urine output <40 ml/day, elevated BUN and creatinine.

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13
Q

What are common causes of ARF in pregnancy?

A

Hypovolaemia (e.g. haemorrhage), sepsis, abruptio placentae, PET, DIC.

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14
Q

What are the classifications of ARF?

A

Pre-renal (hypoperfusion), Renal (intrinsic), Post-renal (obstruction).

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15
Q

What are the phases of acute renal failure?

A

Oliguric phase → Diuretic phase → Recovery phase.

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16
Q

What are clinical signs of the oliguric phase of ARF?

A

↓ urine output, ↑ urea & potassium, metabolic acidosis.

17
Q

What are the signs of the diuretic phase?

A

Large volumes of dilute urine, electrolyte loss.

18
Q

What are the complications of ARF?

A

Cardiac arrhythmias, thrombocytopenia, infections, electrolyte imbalances (hyperK+, hypoNa+, hyperMg2+, hypoCa2+).

19
Q

What are the main causes of death in pregnancy-related ARF?

A

Infection, azotemia, pulmonary oedema, hyperkalaemia-induced arrhythmia.

20
Q

How is ARF treated?

A

Treat cause, surgical correction, fluid/electrolyte balance, insulin-glucose for hyperK+, dialysis.

21
Q

What are physiological changes in the urinary tract during pregnancy?

A

Kidney enlargement, ureter/bladder compression, incomplete bladder emptying, urine less acidic, increased sugars/proteins.

22
Q

What factors contribute to increased UTI risk during pregnancy?

A

Hormonal changes, intercourse, bladder reflux, condom/spermicide use, enlarged uterus.

23
Q

What are the common causative organisms of UTIs in pregnancy?

A

E. coli, S. aureus, Proteus mirabilis, S. saprophyticus, Streptococcus spp., Citrobacter, Klebsiella, Enterobacter, Pseudomonas.

24
Q

Which organism is most commonly associated with UTI in pregnancy?

A

Escherichia coli (50.8%)

25
How can bacteria reach the kidneys to cause pyelonephritis?
By ascending through the ureters from the bladder.