Vasculitis Flashcards
(24 cards)
What are the ACR criteria for Takayasu Arteritis?
Three of 6 of:
10 mm Hg bet arms
Bruit over subclavian
Narrowing in aorta
What are some clinical features of Vasculitis?
Multisystem disease Constitutional S and S. Skin lesions Ischemia Glomerulonephritis, myalgia. Abdominal or testicular pain
What size vessels are effected in Drug induced and serum sickness?
Small Vessels
What size vessels are effected in Henoch Schonlein Purpura?
Small
What size vessels are effected in Classic PAN?
SMall and Med
What size vessels are effected in Giant cell or temporal arteritis?
Large
What size vessels are effected in Kawasaki Syndrome?
Small and MEd
What size vessels are effected in Cryoglobulinemia?
Small
What size vessels are effected in Takayasu Arteritis?
Large
What size vessels are effected in Churg Strauss?
Small and Med
What size vessels are effected in Malignancy associated vasculitis?
Small
What are the Traits of PAN?
Renal Vasc nephropathy
No lung inv
ANCA neg
What are the Traits of MPA?
Glomerulonephritis
1/3 ofcases involve lungs
ANCA pos
How is Henoch Schonlein purpura Dx?
Two of 4 of: Palpable Purpura, Less than 20 yo, Bowel Angina, granulocytes in walls of arterioles or venules
What are the trait of Cryogloulinemia?
Igs that undergo reversible precipitation in the cold
Acral Cyanosis, ulceration
Raynaud’s Phenom
Purpura, Arthralgia, Nephritis, Neuropathy
How is Granulomatosis with Polyangiitis Dx?
Two of 4 of: Nasal or oral Inflammation
Abn Chest Radiograph
Urinary sediment
Granulomatosis inflammation on biopsy
What are the traits of Polymyalgia Rheumatica?
Pelvic and Shoulder Girdle Aching, morning stiffness, Low dose CS, Anemia, Elevated ESR and CRP
What are the Clinical Features of Giant Cell Arteritis?
HEadache, Temporal Artery Abn, Jaw Claudication, WL, Fever, PMR Symptoms
What are the Lab features of Giant Cell Arteritis?
Elevated ESR Elevated CRP Acute phase Reactants Anemia Inc Alk phos
How is Giant Cell Arteritis Classified?
older than 50yo New Headache Temporal Artery Abn Elevated ESR Abn Artery Biopsy
What is Fibromyalgia?
Chronic Pain disorder w/ unknown etiology and unclear pathophys
What is the initial Treatment of FM?
Patient Education: Reassurance, no infection, stress/mood, sleep disorders/ hygeine, EXERCISE
What is the Medical Management for Pain in Symptomatic FM?
Tramadol
Dual re-uptake inhibitors
Anticonvulsants
Topical Agents
What is the Approach to Sleep problems in Symptomatic FM?
Tricyclic AD
Anticonvulsants
Sodium Oxybate
Control Limb movement