W22-L6: Stroke Flashcards Preview

Matt's Block 06 - Neuro block > W22-L6: Stroke > Flashcards

Flashcards in W22-L6: Stroke Deck (16):
1

Definition of stroke

Development of a focal or global neurologic deficit related to a vascular event

2

What are the mechanisms of infarction?

-Inadequate supply due to pump failure
-Inadequate supply due to narrowed vessel lumen
-Vessel occlusion by embolus

3

36 hours after a cerebral infarct what do you see on a gross specimen?

Swelling

4

Days to weeks after an infarct what do you see on a gross specimen?

Liquefactive necrosis

5

Months to years after an infarct what do you see on a gross specimen?

Abscesses where necrosis has occured

6

Why do people with cerebral infarction die?

-Involvement of vital centres
-Cerebral swelling
-Pneumonia
-Cardiovascular disease
-Pulmonary Thromboemolism

7

Causes of intracerebral haemorrhage

-Hypertensive small vessel disease
-Amyloid angiopathy
-Tumour
-Vascualitis

8

What characterises hypertensive haemorrhage?

Presence of small vessel disease (Hyaline arteriolosclerosis)

9

Where does hypertensive haemorrhages usually occur?

-Basal ganglia, thalamus
-Lobar white matter
-Cerebellum
-Pons

10

What is cerebral amyloid angiopathy?

Deposition of Aß amyloid in walls of superficial supratentorial blood vessels

11

What is cerebral amyloid angiopathy associated with?

Superficial haemorrhages and alzheimer's disease

12

Causes of subarachnoid haemorrhage?

-Rupture of saccular aneurysm
-Extension of intracerebral haemorrhage

13

Risk factors for developing saccular aneurysm?

-Sex, age
-Polycystic kidney disease
-Hypertension
-Smoking, alcohol

14

Where do saccular aneurysms occur?

Sites of congenital weakness at arterial bifurcations (anterior circulation more than posterior)

15

What are the favoured sites for saccular aneuryms?

Bifurcation of MCA
Junction of ICA and post. comm artery
-Anterior Comm artery

16

What are complications of aneurysm rupture?

-Subarachnoid haemorrhage
-Cerebral oedema and raised ICP
-Vasospasm and infarction
-Ventricular obstruction causing hydrocephalus

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