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wednesday randoms Flashcards

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1
Q

paracellular barrier

A

tight junctions with claudins and occludins

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2
Q

which fossa is foramen spinosum?

A

middle cranial fossa

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3
Q

CN is middle cranial fossa

A

CN2-6

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4
Q

gastric CA risk factors

A

dietary nitrates, alcohol and tobacco use, H pylori

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5
Q

flucytosine

A

antifungal that targets DNA and RNA synthesis

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6
Q

CN in posterior cranial fossa

A

CN 7-12

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7
Q

caspofungin

A

antifungal that targets the cell wall

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8
Q

epithelial ovarian CA risk factors

A

family hx, infertility, nulliparity, PCOS, endometriosis, BRCA1 or 2 mutation, lynch syndrome, postmenopausal hormone therapy

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9
Q

prostate CA risk factors

A

increasing age, african-american race

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10
Q

amphotericin B and nystatin

A

antifungal that binds ergosterol of cell membrane

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11
Q

liver CA risk factors

A

Hepatitis B &C, liver cirrhosis, hemochromatosis, alfatoxin

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12
Q

aprepitant

A

NK1 R antagonist antiemetic

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13
Q

metoclopromaide

A

D- receptor antagonist antiemetic

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14
Q

pancreas CA risk factors

A

tobacco smoke, obesity

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15
Q

antiemetics for chemotherapy induced emesis

A

metoclopramid, ondansetron, aprepitant

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16
Q

CN in anterior cranial fossa

A

CN1

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17
Q

cellular anchors

A

adheren junction, desmosomes, hemidesmosomes

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18
Q

intercellular connection

A

gap junctions with connexins

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19
Q

colorectal CA risk factors

A

hereditary colorectal CA syndromes, IBD, obesity, charred or fried foods

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20
Q

breast CA risk factors

A

early menarche, late menopause, nulliparity, BRCA mutations

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21
Q

bladder CA risk factors

A

tobacco smoke, occupational exposures (rubber, aromatics, textiles, leather, etc)

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22
Q

griseofulvin

A

antifungal that targets mitosis

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23
Q

azoles

A

antifungal that inhibits synthesis of ergosterol for cell membrane

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24
Q

renal CA risk factors

A

tobacco smoke obesity, hypertension

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25
integrins
proteins of hemidesmosoms; cells connecting to basement membrane
26
scopolamine
antimuscarinic antiemetic
27
cadherins
proteins of desmosomes and adherens junctions
28
diphenhydramine
antihistame antiemetic
29
ondansetron
5HT3 R antagonist antiemetic
30
CA 19-9
pancreatic tumor
31
alpha fetoprotein
HCC, germ cell tumors
32
carcinoembryonic antigen
GI tumors
33
serum marker for germ cell tumors and choriocarcinoma
HCG
34
eye down and out and pupil dilated
oculomotor palsy
35
CN 3 in brainstem?
midline in midbrain
36
can't look up
Parinaud syndrome, posterior midbrain, damage superior colliculi
37
muscle to move eye laterally
CN6, pons
38
3 things to move eyes side to side
CN6, MLF, PPRF = all in pons
39
nucleus ambiguous
muscle 9, 10, 11; in medullar
40
see inferior olivary nucleus?
in medulla!
41
patients tongue deviates to left. where is the lesion?
medial medulla, left CN12 nucleus
42
ASA stroke damages which part of brain
middle medulla
43
which are midline CN?
3, 4, 6, 12 = divide evenly into 12
44
4 midline columns of brainstem?
MLF, motor pathway (corticospinal), motor nucleus (nucleus ambiguous), medial lemniscus
45
unable to look down when looking at nose
CN 4 damage
46
midbrain blood supply
PCA
47
lateral medulla blood supply
PICA
48
medial medulla blood supply
ASA
49
lateral pons blood supply
AICA
50
medial pons blood supply
Basilar artery
51
structures in association with 3rd part of duodenum
SMA
52
part of duodenum that bile duct drains into
2nd; vertical portion
53
cardinal veins form
systemic venous circulation
54
umbilical veins form
portal system
55
caput medusa
paraumbilical veins
56
anorectal varices
superior rectal veins
57
I, AVL, V5, V6
circumflex artery
58
II, III, AVF, V3, V4
right coronary artery
59
V1, V2
LAD
60
cilostazol
X platelet aggregation and vasodilate
61
pseudo allergy with increased leukotrienes
ASA side effect
62
abciximab
Gp2b3a block = NO platelet cross-link
63
ASA
preventative against platelet aggregation
64
Clopidogrel + Ticlodipine
X ADP = NO platelet aggregation
65
Agaratroban + Dabigitraban + Bivalirudin
X thrombine (2a)
66
Fonadaparinux
bind and activates anti-thrombin III
67
vitamin K factors
2, 7, 9, 10, c + s
68
IgG-PFA complex with clots
Heparin Induced Thrombocytopenia (HIT)
69
ranitidine
X H2-R - used in GERD
70
H pylori tx
PPI + clarithromycin + amoxicillin/metronidazole
71
metoclopromide
X D2R, anti-emetic
72
aprepitant
X substance P, NK1R
73
ondansetron
X 5HT23, anti-emetic
74
WPW
PSVT + delta waves
75
Sotalol + Amiodarone
anti-arrhythmic, X K+ in phase 3
76
12-24 hr alcohol withdrawel
seizures
77
48-96 hr alcohol withdrawl
delirium tremens - fever, tachy, HTN, hallucinations

neuro (34 decks)

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