Week 8 Flashcards

1
Q

True/False
Basal Ganglia is important for movement.

A

True

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2
Q

What are the two main neurotransmitters in the basal ganglia?
A. Glutamate and GABA
B. GABA and Dopamine
C. Dopamine and Glutamate
D. None of the Above

A

C. Dopamine and Glutamate

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3
Q

What is a non-motor cortico-basal ganglia-thalamic circuits?
A. Goal-Directed Behavior Circuit
B. Social Behavior Circuit
C. Emotion Circuit
D. All of the Above

A

D. All of the Above

These circuits contribute to the prediction of future events, selecting desired behaviors, preventing undesired behaviors, shifting attention, and spatial working memory.

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4
Q

Which circuit evaluates information for making perceptual decisions, planning, and choosing actions in context?
A. Goal-Directed Behavior Circuit
B. Social Behavior Circuit
C. Emotion/Motivation Circuit
D. Motor Circuit

A

A. Goal-Directed Behavior Circuit

  • Head of the caudate is part of the decision-making circuit that participates in goal-directed behavior
  • This circuit, including the head of the caudate, is not involved in controlling movements
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5
Q

Which circuit recognizes social cues, regulates self-control, and parses out relevant from irrelevant information?
A. Emotion/Motivation Circuit
B. Motor Circuit
C. Social Behavior Circuit
D. Goal-Directed Behavior Circuit

A

C. Social Behavior Circuit

  • Head of the caudate is part of the circuit that recognizes social cues, regulates self-control, and parses out relevant from irrelevant information.
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6
Q

Which circuit has the essential function of seeking rewards?
A. Oculomotor Circuit
B. Social Behavior Circuit
C. Motor Circuit
D. Emotion/Motivation Circuit

A

D. Emotion/Motivation

Also integrates emotions with roles of other circuits. Partially responsible for the perception and experiences of emotions.

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7
Q

Which circuit makes decisions about spatial attention and eye movements?
A. Goal-Directed Behavior Circuit
B. Oculomotor Circuit
C. Emotion/Motivation Circuit
D. Motor Circuit

A

B. Oculomotor Circuit

Determines whether to use fast eye movements to direct attention toward an object

Saccade: Rapid movement of the eyes
Reflexive Prosaccades: move eyes toward an object
Antisaccades Move eyes away from object. Result from more complex interactions than the oculomotor circuit and require inhibition of prosaccade reflex

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8
Q

Which circuit regulates muscle contraction, muscle force, multi-joint movements, and sequencing of movements?
A. Goal-Directed Behavior Circuit
B. Oculomotor Circuit
C. Emotion/Motivation Circuit
D. Motor Circuit

A

D. Motor Circuit

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9
Q

Hypokinetic

A

Too little movement; loss of normal function

Parkinson’s disease is primarily hypokinetic

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10
Q

Hyperkinetic

A

Excessive movement; gain of function not normally present

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11
Q

True/False
Parkinson’s Disease is the least common basal ganglia motor disorder.

A

False
Parkinson’s Disease is the most common basal ganglia motor disorder.

Interferes with both voluntary nd automatic movements

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12
Q

What are the two common subtypes of Parkinson’s Disease?

A

Postural Instability Gait Difficulty (PIGD)
Also known as akinetic/rigid type PD
Tremor-Dominant (TD)

Prevalence of each subtypes is akinetic (50%), TD (40%), and mixed (10%).

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13
Q

What is postural instability gait difficulty characterized by?

Subtype of Parkinson’s Disease

A

Muscular rigidity
Drooping posture
Rhythmic muscular tremors
Mask-like facial expression

People with PIGD PD have difficulty coming to standing from sitting; gait is characterized by:
* flexed posture
* shuffling of feet
* decreased / absent arm swing.

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14
Q

What are the distinctive signs of postural instability gait difficulty?

Subtype of Parkinson’s Disease

A
  • Akinesia/ hypokinesia / bradykinesia / Rigidity
  • Postural unsteadiness
  • Resting tremor
  • Freezing during movement
  • Visuoperceptual impairments
  • Mask-like facial expression
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15
Q

True/False
Postural instability gait difficulty has one hyperkinetic sign: resting tremor.

A

True

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16
Q

What are non-motor impairments for postural instability gait difficulty?

Subtype of Parkinson’s Disease

A
  • Psychosis and autonomic dysfunction
  • Parkinson’s dementia: primarily affects ability to plan, maintain goal direction, and make decisions
17
Q

Describe Tremor-Dominant

Subtype of Parkinson’s Disease

A
  • People with TD PD experience both resting and action tremors
  • Rigidity and slowing of movement are relatively mild
  • Patients with TD PD experience a slower progression of signs and symptoms than those with PIGD PD