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Flashcards in 1.2 Membranes Deck (25):
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3 membrane lipids

Phospholipids
Sphingolipids
Cholesterol

1

4 Characteristics of Phospholipid

1. Glycerol backbone
2. 2 Fatty acids (16-18 carbons) attached to Glycerol
3. Phosphate group attached to Glycerol
4. Alcohol ESTERIFIED to phosphate (4 options)

2

What are the four alcohol options that can be esterified to the phosphate on a phospholipid

1. ethanolamine
2. choline
3. inositol
4. serine

3

Characteristics of Sphingolipids

1. Sphingosine backbone
2. 1 Fatty Acid

4

4 types of structures attached to the available end of a sphingolipid

1. Ceramide (Hydrogen)
2. Sphingomyelin (Phosphocholine)
3. Glucosylcerebroside (Glucose)
4. Ganglioside (Complex Oligosaccharide)

5

A sphingolipid with a phosphate group and choline attached

Sphingomyelin

6

Sphingolipid with a glucose

Glucosylcerebroside

7

Sphingolipid with a hydrogen attached

Ceramide

8

Sphingolipid with a complex oligosaccharide attached

Ganglioside

9

Characteristic of Cholesterol

Found in plasma membrane with hydroxyl group on surface at water surface

10

Function of Cholesterol

Keeps membrane fluid and rigid depending on temperature and characteristics of surroundings

11

Primary leaflet location of Cholesterol

Both cytoplasmic and exoplasmic

12

Primary leaflet location of sphingomyelin

Exoplasmic

13

Primary leaflet location of Phosphotidylserine and Phosphotidylethanolamine

Cytosolic

14

Primary leaflet location of Phosphotidylcholine

exoplasmic

15

Two things that make up lipid rifts

1. Cholesterol
2. Sphingomyelin

16

Function of Lipid Rafts

Function to help concentrate proteins that participate in Signal Transduction pathways

17

2 types of membrane proteins

1. Integral membrane protein
2. Peripheral

18

Name the two protein membrane anchors that are found on the cytosolic side of the membrane

1. Fatty Acyl group covalently attached to a Glycine
2. Isoprene group through Cysteine

19

Name the protein membrane anchor that is found on the exoplasmic surface of the membrane

GPI anchor through Asp

20

What things are permeable to membranes?

Gases and Ethanol (a small uncharged polar molecule)

21

What type of transport uses the gradient of one ion to drive transport of another against its gradients

Secondary Active Transport

22

Which membrane transport requires ATP to push a molecule against its electrochemical gradient?

Primary Active Transport

23

Name the four classes of ATP powered transport proteins

1. P-class pumps
2. V-class proton pumps
3. F-class proton pumps
4. ABC superfamily (moves molecules vs ions)

24

Name the three ATP powered transport proteins that move ions

P-class pumps
V-class proton pumps
F-class proton pumps