3.8 Obese Metabolism Flashcards Preview

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Flashcards in 3.8 Obese Metabolism Deck (19):
0

Individuals with upper or lower body fat have greater health risks

Upper body fat has greater health risks than pear fat

1

Weight gain or weight loss affects adipose cells how?

Affects the size but not the number of cells

2

T or F, Obesity is a disease of chronic inflammation

True

3

What is the product of the ob gene

Leptin

4

How much of leptin is released in the body?

In proportion to mass of tissue

5

What two things occur during a secretion of leptin

Decrease in apetite
Increase in energy expenditure

6

Signals of feeding whether stimulatory or inhibitory are integrated and relayed in what portion of the CNS

Hypothalamus

7

Overeating and obesity are associated with damage to what two things?

Ventromedial Nucleus
Paraventricular Nucleus

8

Weight loss and Anorexia related to what region of CNS?

Lateral Hypothalamic regions

9

Weight is regulated by a balance between stimulation and inhibition of what two types of neurons in the hypothalamus

Orexigenic
Anorexigenic

10

Orexigenic neurons stimulate what?

Eating and inactivity

11

Anorexigenic neurons function?

They suppress eating

12

What two things are released by orexigenic neurons of the hypothalamus

NPY (nucleotide Y)
AgRP (Agouti related protein)

13

Anorexigenic neurons release what two things?

POMC (Pro-Opiomelanocortin)
CART (Cocaine and Amphetamine regulated Transcript)

14

Leptin reduces what and stimulates what?

Reduces fuel intake
Stimulates energy expenditure

15

Leptin inhibits appetite by:?

Increasing activity of Anorexigenic neurons
Decreasing activity of Orexigenic neurons

16

T or F, Insulin acts on receptors in the hypothalamus to inhibit feeding just as leptin?

True

17

Function of Ghrelin

Appetite Inducing peptide hormone

18

How does Ghrelin carry out its function metabolically

Ghrelin binds to and stimulates the NPY/AgRP/GABA neurons which stimulates an Orexigenic response to seek food